Trait
Displacement of one backbone compared to another
Clinical name: Spondylolisthesis
Complete bilateral fractures of the pars interarticularis resulting in the anterior slippage of the vertebra.
Summary
- Also called
- Slipped backbone, Spondylolithesis
- Body system
- Abnormality of the musculoskeletal system
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
Read the genes linked to Displacement of one backbone compared to another, and the rest of your genome, with one test.
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Get my Genome Test20 genes linked to Displacement of one backbone compared to another
Changes in these genes cause rare conditions in which Displacement of one backbone compared to another is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| GNPTABN-acetylglucosamine-1-phosphate transferase subunits alpha and beta | Always | In 1 condition |
| PABPN1poly(A) binding protein nuclear 1 | Very often (80–99%) | In 1 condition |
| BMP2bone morphogenetic protein 2 | Often (30–79%) | In 1 condition |
| SMAD3SMAD family member 3 | Often (30–79%) | In 2 conditions |
| TGFBR1transforming growth factor beta receptor 1 | Often (30–79%) | In 1 condition |
| COL2A1collagen type II alpha 1 chain | Sometimes (5–29%) | In 1 condition |
| CTSKcathepsin K | Sometimes (5–29%) | In 2 conditions |
| KANSL1KAT8 regulatory NSL complex subunit 1 | Sometimes (5–29%) | In 1 condition |
| LMX1BLIM homeobox transcription factor 1 beta | Sometimes (5–29%) | In 1 condition |
| MYH3myosin heavy chain 3 | Sometimes (5–29%) | In 1 condition |
| TGFB2transforming growth factor beta 2 | Sometimes (5–29%) | In 1 condition |
| ZFXzinc finger protein X-linked | Sometimes (5–29%) | In 1 condition |
| TGFB3transforming growth factor beta 3 | Rarely (1–4%) | In 1 condition |
| AGAaspartylglucosaminidase | Not recorded | In 1 condition |
| FBN1fibrillin 1 | Not recorded | In 1 condition |
| IDUAalpha-L-iduronidase | Not recorded | In 1 condition |
| MAN2B1mannosidase alpha class 2B member 1 | Not recorded | In 1 condition |
| RUNX2RUNX family transcription factor 2 | Not recorded | In 1 condition |
| TGFBR2transforming growth factor beta receptor 2 | Not recorded | In 1 condition |
| ZNF469zinc finger protein 469 | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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