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Gene

SLC25A36

solute carrier family 25 member 36

Summary

Cytogenetic location
3q23
Coordinates
Chromosome 3: 140,941,836–140,980,995 (GRCh38)
Exons
7 exons across 39.2 kb
Protein
311 amino acids
Inheritance
Autosomal recessive
Also known as
FLJ10618, PNC2
MANE Select transcript
ENST00000324194.12NM_001104647.3
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated report relevant to this gene

  • Hyperinsulinism

    • Hyperinsulinemic hypoglycemia, familial, 8Autosomal recessive

      Familial hyperinsulinaemic hypoglycaemia caused by SLC25A36 variants.

      • 1 GenCC submitter rates it definitive or strong

Inheritance

Autosomal recessive
It takes a changed copy from each parent. With one, you are a carrier and usually unaffected; when both parents are carriers, each child has a one-in-four chance of inheriting two.

How SLC25A36 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 3, with a bracket where SLC25A36 sits. SLC25A36 and 5 genes near it on chromosome 3, from 140,461,416 to 141,461,415.Chromosome 33q23p26.3p26.2p26.1p25.3p25.2p25.1p24.3p24.2p24.1p23p22.3p22.2p22.1p21.33p21.32p21.31p21.2p21.1p14.3p14.2p14.1p13p12.3p12.2p12.1p11.2p11.1q11.1q11.2q12.1q12.2q12.3q13.11q13.12q13.13q13.2q13.31q13.32q13.33q21.1q21.2q21.3q22.1q22.2q22.3q23q24q25.1q25.2q25.31q25.32q25.33q26.1q26.2q26.31q26.32q26.33q27.1q27.2q27.3q28q29140.6 Mb140.8 Mb141 Mb141.2 Mb141.4 MbCLSTN2: 139,935,185–140,577,397, forward strandCLSTN2TRIM42: 140,678,064–140,701,150, forward strandTRIM42SLC25A36: 140,941,836–140,980,995, forward strandSLC25A36SPSB4: 141,050,744–141,148,613, forward strandSPSB4PXYLP1: 141,228,726–141,367,753, forward strandPXYLP1ZBTB38: 141,324,154–141,449,792, forward strandZBTB38Diagram of SLC25A36: 7 exons on the forward strand of chromosome 3Exon 1: 140,941,836–140,942,095, 260 basesExon 2: 140,956,527–140,956,691, 165 basesExon 3: 140,959,463–140,959,540, 78 basesExon 4: 140,963,127–140,963,227, 101 basesExon 5: 140,970,927–140,970,993, 67 basesExon 6: 140,973,716–140,974,005, 290 basesExon 7: 140,976,260–140,980,995, 4,736 bases12345675′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 5.7 kb of the gene's 39.2 kb; 936 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • GenCC and ClinGen, released 2026-10-16: which conditions the gene is linked to, and how strongly.
  • The ACMG secondary findings list, SF v3.2.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). SLC25A36 gene: solute carrier family 25 member 36. Retrieved 16 October 2026, from https://dantelabs.com/genes/slc25a36

Vancouver

Dante Labs. SLC25A36 gene: solute carrier family 25 member 36 [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/slc25a36

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