Traits

Traits linked to SGCB

sarcoglycan beta

The Human Phenotype Ontology links 22 traits to SGCB, by body system: features seen in people with one of the gene's rare conditions.

Abnormality of limbs

Trait	How often it is seen
Increased size of calf muscles	Often (30–79%)
Pelvic girdle muscle weakness	Often (30–79%)
Calf muscle pseudohypertrophy	Sometimes (5–29%)
Limb-girdle muscle weakness	Not recorded
Pelvic girdle muscle atrophy	Not recorded
Shoulder girdle muscle wasting	Not recorded
Winged shoulder blade	Not recorded

Abnormality of the musculoskeletal system

Trait	How often it is seen
Gowers sign	Often (30–79%)
Increased variability in muscle fiber diameter	Often (30–79%)
Muscle tissue disease	Often (30–79%)
Muscular dystrophy	Not recorded
Wasting of muscles near the body	Not recorded

Abnormality of the nervous system

Trait	How often it is seen
Loss of ability to walk	Always
Abnormal gait	Often (30–79%)
Delayed speech and language development	Often (30–79%)
Waddling gait	Often (30–79%)
Wide based walk	Often (30–79%)

Abnormality of the cardiovascular system

Trait	How often it is seen
Disease of the heart muscle	Sometimes (5–29%)
Stretched and thinned heart muscle	Sometimes (5–29%)

Laboratory abnormality

Trait	How often it is seen
Elevated blood creatine phosphokinase	Always
Myoglobinuria	Sometimes (5–29%)

Abnormality of head or neck

Trait	How often it is seen
Myopathic facies	Often (30–79%)

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Where this comes from

The Human Phenotype Ontology, release 2026-09-01: the traits linked to SGCB and how often each is seen. Find out more at hpo.jax.org.

One test. A lifetime of answers.

From $449Free shipping · Results in 6–8 weeks

Get my Genome Test