Traits

Traits linked to RORA

RAR related orphan receptor A

The Human Phenotype Ontology links 27 traits to RORA, by body system: features seen in people with one of the gene's rare conditions.

Abnormality of the nervous system

Trait	How often it is seen
Ataxia	Often (30–79%)
Autism spectrum disorder	Often (30–79%)
Delayed ability to walk	Often (30–79%)
Delayed speech and language development	Often (30–79%)
Epilepsy	Often (30–79%)
Tremor	Often (30–79%)
Abnormal pyramidal sign	Sometimes (5–29%)
Borderline personality disorder	Sometimes (5–29%)
Eyelid myoclonus	Sometimes (5–29%)
Incoordination	Sometimes (5–29%)
Pontocerebellar atrophy	Sometimes (5–29%)
Small cerebellum	Sometimes (5–29%)
Spina bifida occulta	Sometimes (5–29%)
Underdevelopment of part of brain called corpus callosum	Sometimes (5–29%)
Global developmental delay	Not recorded
Intellectual disability	Not recorded
Motor delay	Not recorded

Abnormality of the eye

Trait	How often it is seen
Cross-eyed	Often (30–79%)
Farsightedness	Sometimes (5–29%)
Involuntary, rapid, rhythmic eye movements	Sometimes (5–29%)
Inward turning cross eyed	Sometimes (5–29%)
Lazy eye	Sometimes (5–29%)
Oculomotor apraxia	Sometimes (5–29%)

Abnormality of the genitourinary system

Trait	How often it is seen
Hydronephrosis	Sometimes (5–29%)
Undescended testes	Sometimes (5–29%)

Abnormality of the digestive system

Trait	How often it is seen
Chronic constipation	Sometimes (5–29%)

Abnormality of the musculoskeletal system

Trait	How often it is seen
Generalized decreased muscle tone	Often (30–79%)

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Where this comes from

The Human Phenotype Ontology, release 2026-09-01: the traits linked to RORA and how often each is seen. Find out more at hpo.jax.org.

One test. A lifetime of answers.

From $449Free shipping · Results in 6–8 weeks

Get my Genome Test