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Gene

PLAA

phospholipase A2 activating protein

Summary

Cytogenetic location
9p21.2
Coordinates
Chromosome 9: 26,903,372–26,947,242 (GRCh38)
Exons
14 exons across 43.9 kb
Protein
795 amino acids
Also known as
PLAP, PLA2P, FLJ11281, FLJ12699, DOA1
MANE Select transcript
ENST00000397292.8NM_001031689.3
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads PLAA yet. The test sequences your whole genome, so your data includes it all the same.

How PLAA is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 9, with a bracket where PLAA sits. PLAA and 6 genes near it on chromosome 9, from 26,425,307 to 27,425,306.Chromosome 99p21.2p24.3p24.2p24.1p23p22.3p22.2p22.1p21.3p21.2p21.1p13.3p13.2p13.1p12p11.2p11.1q11q12q13q21.11q21.12q21.13q21.2q21.31q21.32q21.33q22.1q22.2q22.31q22.32q22.33q31.1q31.2q31.3q32q33.1q33.2q33.3q34.11q34.12q34.13q34.2q34.326.6 Mb26.8 Mb27 Mb27.2 Mb27.4 MbCAAP1: 26,837,785–26,892,824, reverse strandCAAP1PLAA: 26,903,372–26,947,242, reverse strandPLAAIFT74: 26,947,039–27,066,198, forward strandIFT74LRRC19: 26,993,136–27,005,709, reverse strandLRRC19TEK: 27,109,030–27,232,092, forward strandTEKEQTN: 27,284,654–27,297,150, reverse strandEQTNMOB3B: 27,325,209–27,529,829, reverse strandMOB3BDiagram of PLAA: 14 exons on the reverse strand of chromosome 9Exon 14: 1 known disease-causing siteExon 13: 1 known disease-causing siteExon 12: 1 known disease-causing siteExon 6: 1 known disease-causing siteExon 2: 1 known disease-causing siteExon 1: 1 known disease-causing siteExon 14: 26,903,372–26,906,076, 2,705 basesExon 13: 26,907,834–26,907,998, 165 basesExon 12: 26,910,338–26,910,439, 102 basesExon 11: 26,913,879–26,913,947, 69 basesExon 10: 26,917,097–26,917,165, 69 basesExon 9: 26,919,310–26,919,529, 220 basesExon 8: 26,920,227–26,920,384, 158 basesExon 7: 26,923,178–26,923,347, 170 basesExon 6: 26,925,825–26,925,960, 136 basesExon 5: 26,926,393–26,926,560, 168 basesExon 4: 26,928,100–26,928,220, 121 basesExon 3: 26,928,308–26,928,408, 101 basesExon 2: 26,935,013–26,935,206, 194 basesExon 1: 26,946,897–26,947,242, 346 bases141210864215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 4.7 kb of the gene's 43.9 kb; 2,388 of those bases code for the protein.

How a genome test reads PLAA

6

positions in PLAA where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 43.9 kb of PLAA, introns included, not only the 4.7 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). PLAA gene: phospholipase A2 activating protein. Retrieved 17 October 2026, from https://dantelabs.com/genes/plaa

Vancouver

Dante Labs. PLAA gene: phospholipase A2 activating protein [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/plaa

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