Trait
Canker sore
Clinical name: Aphthous ulcer
Oral aphthous ulcers typically present as painful, sharply circumscribed fibrin-covered mucosal defects with a hyperemic border.
Summary
- Body system
- Abnormality of head or neck
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
Read the genes linked to Canker sore, and the rest of your genome, with one test.
From $449Free shipping · Results in 6–8 weeks
Get my Genome Test9 genes linked to Canker sore
Changes in these genes cause rare conditions in which Canker sore is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| IL21interleukin 21 | Always | In 1 condition |
| NLRP3NLR family pyrin domain containing 3 | Always | In 1 condition |
| SEC61A1SEC61 translocon subunit alpha 1 | Always | In 1 condition |
| SLC19A1solute carrier family 19 member 1 | Always | In 1 condition |
| SASH3SAM and SH3 domain containing 3 | Often (30–79%) | In 1 condition |
| ADA2adenosine deaminase 2 | Sometimes (5–29%) | In 1 condition |
| MEFVMEFV innate immunity regulator, pyrin | Sometimes (5–29%) | In 1 condition |
| IL6interleukin 6 | Not recorded | In 1 condition |
| NOD2nucleotide binding oligomerization domain containing 2 | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
One test. A lifetime of answers.
From $449Free shipping · Results in 6–8 weeks