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Gene

HSD11B1

hydroxysteroid 11-beta dehydrogenase 1

Summary

Cytogenetic location
1q32.2
Coordinates
Chromosome 1: 209,704,846–209,734,929 (GRCh38)
Exons
6 exons across 30.1 kb
Protein
292 amino acids
Also known as
SDR26C1
Previous symbols
HSD11B, HSD11
MANE Select transcript
ENST00000367027.5NM_005525.4
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads HSD11B1 yet. The test sequences your whole genome, so your data includes it all the same.

How HSD11B1 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 1, with a bracket where HSD11B1 sits. HSD11B1 and 9 genes near it on chromosome 1, from 209,219,888 to 210,219,887.Chromosome 11q32.2p36.33p36.32p36.31p36.23p36.22p36.21p36.13p36.12p36.11p35.3p35.2p35.1p34.3p34.2p34.1p33p32.3p32.2p32.1p31.3p31.2p31.1p22.3p22.2p22.1p21.3p21.2p21.1p13.3p13.2p13.1p12p11.2p11.1q11q12q21.1q21.2q21.3q22q23.1q23.2q23.3q24.1q24.2q24.3q25.1q25.2q25.3q31.1q31.2q31.3q32.1q32.2q32.3q41q42.11q42.12q42.13q42.2q42.3q43q44209.4 Mb209.6 Mb209.8 Mb210 Mb210.2 MbCAMK1G: 209,583,714–209,613,939, forward strandCAMK1GLAMB3: 209,614,870–209,653,146, reverse strandLAMB3G0S2: 209,675,405–209,676,390, forward strandG0S2HSD11B1: 209,704,846–209,734,929, forward strandHSD11B1TRAF3IP3: 209,755,573–209,782,320, forward strandTRAF3IP3C1orf74: 209,779,208–209,784,620, reverse strandC1orf74: 209,779,629–209,806,179, reverse strandIRF6: 209,784,984–209,806,217, reverse strandIRF6UTP25: 209,827,956–209,857,565, forward strandUTP25SYT14: 209,900,923–210,171,389, forward strandSYT14Diagram of HSD11B1: 6 exons on the forward strand of chromosome 1Exon 1: 209,704,846–209,705,030, 185 basesExon 2: 209,705,811–209,705,941, 131 basesExon 3: 209,706,709–209,706,820, 112 basesExon 4: 209,706,943–209,707,128, 186 basesExon 5: 209,732,436–209,732,579, 144 basesExon 6: 209,734,304–209,734,929, 626 bases12465′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 1.4 kb of the gene's 30.1 kb; 879 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.

Cite this page

APA

Dante Labs. (n.d.). HSD11B1 gene: hydroxysteroid 11-beta dehydrogenase 1. Retrieved 16 October 2026, from https://dantelabs.com/genes/hsd11b1

Vancouver

Dante Labs. HSD11B1 gene: hydroxysteroid 11-beta dehydrogenase 1 [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/hsd11b1

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