Trait
Increased circulating androgen concentration
An elevation of the blood concentration of an androgen, that is, of a steroid hormone that controls development and maintenance of masculine characteristics. The androgens include testosterone and Dehydroepiandrosterone.
Summary
- Also called
- Hyperandrogenemia, Increased circulating androgen level
- Body system
- Abnormality of the endocrine system
Reference genomeGRCh38hg38
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Get my Genome Test12 genes linked to Increased circulating androgen concentration
Changes in these genes cause rare conditions in which Increased circulating androgen concentration is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| INSRinsulin receptor | Always | In 2 conditions |
| CYP11B1cytochrome P450 family 11 subfamily B member 1 | Very often (80–99%) | In 1 condition |
| CDKN2Acyclin dependent kinase inhibitor 2A | Often (30–79%) | In 1 condition |
| CTNNB1catenin beta 1 | Often (30–79%) | In 1 condition |
| H6PDhexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase | Often (30–79%) | In 1 condition |
| HSD11B1hydroxysteroid 11-beta dehydrogenase 1 | Often (30–79%) | In 1 condition |
| PRKAR1Aprotein kinase cAMP-dependent type I regulatory subunit alpha | Often (30–79%) | In 1 condition |
| TERTtelomerase reverse transcriptase | Often (30–79%) | In 1 condition |
| TP53tumor protein p53 | Often (30–79%) | In 1 condition |
| ZNRF3zinc and ring finger 3 | Often (30–79%) | In 1 condition |
| ALMS1ALMS1 centrosome and basal body associated protein | Sometimes (5–29%) | In 1 condition |
| ALG6ALG6 alpha-1,3-glucosyltransferase | Rarely (1–4%) | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
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Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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