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Trait

Bicoronal synostosis

Synostosis affecting the right and the left coronal suture.

HPO HP:0011318

Summary

Also called
Bilateral coronal craniosynostosis, Bilateral coronal suture craniosynostosis, Bilateral coronal suture synostosis
Body system
Abnormality of head or neckAbnormality of the musculoskeletal system

13 genes linked to Bicoronal synostosis

Changes in these genes cause rare conditions in which Bicoronal synostosis is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.

GeneHow often it is seenConditions
AHDC1AT-hook DNA binding motif containing 1AlwaysIn 1 condition
AMOTL1angiomotin like 1AlwaysIn 1 condition
FGFR1fibroblast growth factor receptor 1Very often (80–99%)In 1 condition
FGFR2fibroblast growth factor receptor 2Very often (80–99%)In 1 condition
DHRS3dehydrogenase/reductase 3Often (30–79%)In 1 condition
ERFETS2 repressor factorOften (30–79%)In 1 condition
H4C9H4 clustered histone 9Often (30–79%)In 1 condition
TCF12transcription factor 12Often (30–79%)In 2 conditions
ZIC1Zic family zinc finger 1Often (30–79%)In 2 conditions
MSX2msh homeobox 2Sometimes (5–29%)In 1 condition
SCUBE3signal peptide, CUB domain and EGF like domain containing 3Sometimes (5–29%)In 1 condition
SMOsmoothened, frizzled class receptorSometimes (5–29%)In 1 condition
RECQL4RecQ like helicase 4Not recordedIn 1 condition

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Broader traits

Coronal craniosynostosis

Where this comes from

  • The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

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