Trait
Thyroid gland inflammation
Clinical name: Thyroiditis
Inflammation of the thyroid gland.
Summary
Reference genomeGRCh38hg38
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Get my Genome Test38 genes linked to Thyroid gland inflammation
Changes in these genes cause rare conditions in which Thyroid gland inflammation is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| IL2RAinterleukin 2 receptor subunit alpha | Always | In 1 condition |
| RNU6ATACRNA, U6atac small nuclear | Always | In 1 condition |
| TRAF3TNF receptor associated factor 3 | Always | In 1 condition |
| FOXP3forkhead box P3 | Often (30–79%) | In 1 condition |
| ITCHitchy E3 ubiquitin protein ligase | Often (30–79%) | In 1 condition |
| NLRP1NLR family pyrin domain containing 1 | Often (30–79%) | In 1 condition |
| SLC37A4solute carrier family 37 member 4 | Often (30–79%) | In 1 condition |
| STAT1signal transducer and activator of transcription 1 | Often (30–79%) | In 1 condition |
| ADAadenosine deaminase | Sometimes (5–29%) | In 1 condition |
| CASP10caspase 10 | Sometimes (5–29%) | In 1 condition |
| CHD7chromodomain helicase DNA binding protein 7 | Sometimes (5–29%) | In 1 condition |
| CTLA4cytotoxic T-lymphocyte associated protein 4 | Sometimes (5–29%) | In 1 condition |
| DCLRE1CDNA cross-link repair 1C | Sometimes (5–29%) | In 1 condition |
| FASFas cell surface death receptor | Sometimes (5–29%) | In 1 condition |
| FASLGFas ligand | Sometimes (5–29%) | In 1 condition |
| FOXN1forkhead box N1 | Sometimes (5–29%) | In 1 condition |
| GPR35G protein-coupled receptor 35 | Sometimes (5–29%) | In 1 condition |
| IL2RGinterleukin 2 receptor subunit gamma | Sometimes (5–29%) | In 1 condition |
| IL7Rinterleukin 7 receptor | Sometimes (5–29%) | In 1 condition |
| LRBALPS responsive beige-like anchor protein | Sometimes (5–29%) | In 1 condition |
| MST1macrophage stimulating 1 | Sometimes (5–29%) | In 1 condition |
| NUDCD3NudC domain containing 3 | Sometimes (5–29%) | In 1 condition |
| PSMB10proteasome 20S subunit beta 10 | Sometimes (5–29%) | In 1 condition |
| RAG1recombination activating 1 | Sometimes (5–29%) | In 1 condition |
| RAG2recombination activating 2 | Sometimes (5–29%) | In 1 condition |
| RMRPRNA component of mitochondrial RNA processing endoribonuclease | Sometimes (5–29%) | In 1 condition |
| SEMA4Dsemaphorin 4D | Sometimes (5–29%) | In 1 condition |
| SOCS1suppressor of cytokine signaling 1 | Sometimes (5–29%) | In 1 condition |
| STAT5Bsignal transducer and activator of transcription 5B | Sometimes (5–29%) | In 1 condition |
| TCF4transcription factor 4 | Sometimes (5–29%) | In 1 condition |
| APCAPC regulator of Wnt signaling pathway | Rarely (1–4%) | In 1 condition |
| HLA-DQA1major histocompatibility complex, class II, DQ alpha 1 | Not recorded | In 1 condition |
| HLA-DQB1major histocompatibility complex, class II, DQ beta 1 | Not recorded | In 1 condition |
| NFKB2nuclear factor kappa B subunit 2 | Not recorded | In 1 condition |
| PIK3CAphosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | Not recorded | In 1 condition |
| PTENphosphatase and tensin homolog | Not recorded | In 1 condition |
| TGthyroglobulin | Not recorded | In 1 condition |
| ZFATzinc finger and AT-hook domain containing | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
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Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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