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Gene

TNNI2

troponin I2, fast skeletal type

Summary

Cytogenetic location
11p15.5
Coordinates
Chromosome 11: 1,838,981–1,841,678 (GRCh38)
Exons
8 exons across 2.7 kb
Protein
182 amino acids
Also known as
FSSV, DA2B, fsTnI
Previous symbols
AMCD2B
MANE Select transcript
ENST00000381911.6NM_003282.4
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads TNNI2 yet. The test sequences your whole genome, so your data includes it all the same.

How TNNI2 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
Chromosome 11, with a bracket where TNNI2 sits. TNNI2 and 26 genes near it on chromosome 11, from 1,340,330 to 2,340,329.Chromosome 1111p15.5p15.5p15.4p15.3p15.2p15.1p14.3p14.2p14.1p13p12p11.2p11.12p11.11q11q12.1q12.2q12.3q13.1q13.2q13.3q13.4q13.5q14.1q14.2q14.3q21q22.1q22.2q22.3q23.1q23.2q23.3q24.1q24.2q24.3q251.4 Mb1.6 Mb1.8 Mb2 Mb2.2 MbBRSK2: 1,389,899–1,462,689, forward strandBRSK2MOB2: 1,469,457–1,501,247, reverse strandMOB2DUSP8: 1,554,051–1,573,076, reverse strandKRTAP5-1: 1,584,342–1,585,283, reverse strandKRTAP5-2: 1,597,177–1,598,294, reverse strandKRTAP5-2KRTAP5-3: 1,607,565–1,608,463, reverse strandKRTAP5-3KRTAP5-4: 1,620,958–1,622,138, reverse strandKRTAP5-4KRTAP5-5: 1,629,775–1,630,930, forward strandKRTAP5-5KRTAP5-6: 1,697,195–1,697,755, forward strandKRTAP5-6IFITM10: 1,732,406–1,750,607, reverse strandIFITM10: 1,734,821–1,763,954, reverse strandCTSD: 1,752,752–1,764,573, reverse strandCTSDSYT8: 1,828,307–1,837,521, forward strandSYT8TNNI2: 1,838,981–1,841,678, forward strandTNNI2LSP1: 1,850,904–1,892,267, forward strandLSP1PRR33: 1,888,078–1,917,713, reverse strandPRR33TNNT3: 1,919,456–1,938,711, forward strandTNNT3MRPL23: 1,947,278–2,014,943, forward strandMRPL23H19: 1,995,165–2,004,552, reverse strandH19: 2,129,112–2,149,603, reverse strandIGF2: 2,129,112–2,158,596, reverse strandIGF2INS-IGF2: 2,132,538–2,161,209, reverse strandINS-IGF2INS: 2,159,779–2,161,221, reverse strandINSTH: 2,163,929–2,171,968, reverse strandASCL2: 2,268,498–2,271,040, reverse strandASCL2C11orf21: 2,295,628–2,303,180, reverse strandC11orf21TSPAN32: 2,301,981–2,318,204, forward strandTSPAN32Diagram of TNNI2: 8 exons on the forward strand of chromosome 11Exon 7: 1 known disease-causing siteExon 8: 8 known disease-causing sitesExon 1: 1,838,981–1,839,033, 53 basesExon 2: 1,839,675–1,839,704, 30 basesExon 3: 1,839,849–1,839,855, 7 basesExon 4: 1,840,403–1,840,444, 42 basesExon 5: 1,840,528–1,840,656, 129 basesExon 6: 1,840,819–1,840,908, 90 basesExon 7: 1,841,031–1,841,207, 177 basesExon 8: 1,841,456–1,841,678, 223 bases123456785′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 0.8 kb of the gene's 2.7 kb; 549 of those bases code for the protein.

How a genome test reads TNNI2

10

positions in TNNI2 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 2.7 kb of TNNI2, introns included, not only the 0.8 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). TNNI2 gene: troponin I2, fast skeletal type. Retrieved 17 October 2026, from https://dantelabs.com/genes/tnni2

Vancouver

Dante Labs. TNNI2 gene: troponin I2, fast skeletal type [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/tnni2

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