Trait
Brain inflammation
Clinical name: Infectious encephalitis
A disorder of the brain caused by an infectious agent that presents with fever, headache, and an altered level of consciousness. There may also be focal or multifocal neurologic deficits, and focal or generalized seizure activity.
Summary
Reference genomeGRCh38hg38
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Get my Genome Test33 genes linked to Brain inflammation
Changes in these genes cause rare conditions in which Brain inflammation is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| BCL10BCL10 immune signaling adaptor | Always | In 1 condition |
| L2HGDHL-2-hydroxyglutarate dehydrogenase | Very often (80–99%) | In 1 condition |
| TMEM70transmembrane protein 70 | Very often (80–99%) | In 1 condition |
| ATRXATRX chromatin remodeler | Sometimes (5–29%) | In 1 condition |
| C4Acomplement C4A (Chido/Rodgers blood group) | Sometimes (5–29%) | In 1 condition |
| CCR1C-C motif chemokine receptor 1 | Sometimes (5–29%) | In 1 condition |
| CD4CD4 molecule | Sometimes (5–29%) | In 1 condition |
| CLTRNcollectrin, amino acid transport regulator | Sometimes (5–29%) | In 1 condition |
| ERAP1endoplasmic reticulum aminopeptidase 1 | Sometimes (5–29%) | In 1 condition |
| FASFas cell surface death receptor | Sometimes (5–29%) | In 1 condition |
| HLA-Bmajor histocompatibility complex, class I, B | Sometimes (5–29%) | In 1 condition |
| IFNGR1interferon gamma receptor 1 | Sometimes (5–29%) | In 1 condition |
| IL10interleukin 10 | Sometimes (5–29%) | In 1 condition |
| IL12Ainterleukin 12A | Sometimes (5–29%) | In 1 condition |
| IL12A-AS1IL12A antisense RNA 1 | Sometimes (5–29%) | In 1 condition |
| IL23Rinterleukin 23 receptor | Sometimes (5–29%) | In 1 condition |
| IRF4interferon regulatory factor 4 | Sometimes (5–29%) | In 1 condition |
| KLRC4killer cell lectin like receptor C4 | Sometimes (5–29%) | In 1 condition |
| LBRlamin B receptor | Sometimes (5–29%) | In 1 condition |
| MEFVMEFV innate immunity regulator, pyrin | Sometimes (5–29%) | In 1 condition |
| PRF1perforin 1 | Sometimes (5–29%) | In 2 conditions |
| SLC6A19solute carrier family 6 member 19 | Sometimes (5–29%) | In 1 condition |
| STAT1signal transducer and activator of transcription 1 | Sometimes (5–29%) | In 1 condition |
| STAT4signal transducer and activator of transcription 4 | Sometimes (5–29%) | In 1 condition |
| STX11syntaxin 11 | Sometimes (5–29%) | In 1 condition |
| STXBP2syntaxin binding protein 2 | Sometimes (5–29%) | In 1 condition |
| TLR4toll like receptor 4 | Sometimes (5–29%) | In 1 condition |
| UBAC2UBA domain containing 2 | Sometimes (5–29%) | In 1 condition |
| UNC13Dunc-13 homolog D | Sometimes (5–29%) | In 1 condition |
| BTKBruton tyrosine kinase | Not recorded | In 2 conditions |
| CIITAclass II major histocompatibility complex transactivator | Not recorded | In 1 condition |
| SH2D1ASH2 domain containing 1A | Not recorded | In 1 condition |
| XIAPX-linked inhibitor of apoptosis | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
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Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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