Trait
Hypercoagulability
An abnormality of coagulation associated with an increased risk of thrombosis.
Summary
- Also called
- Blood hyperviscosity, Thrombophilia
Reference genomeGRCh38hg38
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Get my Genome Test18 genes linked to Hypercoagulability
Changes in these genes cause rare conditions in which Hypercoagulability is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| PROS1protein S | Always | In 2 conditions |
| SOX17SRY-box transcription factor 17 | Always | In 1 condition |
| ANK1ankyrin 1 | Often (30–79%) | In 1 condition |
| DLDdihydrolipoamide dehydrogenase | Often (30–79%) | In 1 condition |
| EPB42erythrocyte membrane protein band 4.2 | Often (30–79%) | In 1 condition |
| GATA2GATA binding protein 2 | Often (30–79%) | In 1 condition |
| HBBhemoglobin subunit beta | Often (30–79%) | In 1 condition |
| MYD88MYD88 innate immune signal transduction adaptor | Often (30–79%) | In 1 condition |
| SLC4A1solute carrier family 4 member 1 (Diego blood group) | Often (30–79%) | In 1 condition |
| SPTA1spectrin alpha, erythrocytic 1 | Often (30–79%) | In 1 condition |
| SPTBspectrin beta, erythrocytic | Often (30–79%) | In 1 condition |
| AGGF1angiogenic factor with G-patch and FHA domains 1 | Sometimes (5–29%) | In 1 condition |
| PIK3CAphosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | Sometimes (5–29%) | In 1 condition |
| F5coagulation factor V | Not recorded | In 1 condition |
| F9coagulation factor IX | Not recorded | In 1 condition |
| HRGhistidine rich glycoprotein | Not recorded | In 1 condition |
| PROCprotein C, inactivator of coagulation factors Va and VIIIa | Not recorded | In 2 conditions |
| THBDthrombomodulin | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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