Tratto
Waddling gait
Weakness of the hip girdle and upper thigh muscles, for instance in myopathies, leads to an instability of the pelvis on standing and walking. If the muscles extending the hip joint are affected, the posture in that joint becomes flexed and lumbar lordosis increases. The patients usually have difficulties standing up from a sitting position. Due to weakness in the gluteus medius muscle, the hip on the side of the swinging leg drops with each step (referred to as Trendelenburg sign). The gait appears waddling. The patients frequently attempt to counteract the dropping of the hip on the swinging side by bending the trunk towards the side which is in the stance phase (in the German language literature this is referred to as Duchenne sign). Similar gait patterns can be caused by orthopedic conditions when the origin and the insertion site of the gluteus medius muscle are closer to each other than normal, for instance due to a posttraumatic elevation of the trochanter or pseudarthrosis of the femoral neck.
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- Detto anche
- Waddling walk
- Sistema corporeo
- Abnormality of the nervous system
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Ottieni il mio Genome Test72 condition reports read genes linked to this trait
Dante Labs condition reports look at the genes behind groups of inherited conditions, read from one whole-genome test. Each page says which conditions and genes a report covers, how it is read and what it cannot tell you.
- Congenital MyopathiesReads 17 of these genesACTA1BIN1CFL2MYPNRYR1SPEGAbout this report →
- Limb-Girdle Muscular DystrophyReads 16 of these genesLMNATRIM32ANO5DAG1DNAJB6FKRPAbout this report →
- Epiphyseal and Spondyloepiphyseal DysplasiasReads 8 of these genesCOL2A1MATN3COMPSLC26A2COL9A1COL9A2About this report →
- Congenital Muscular DystrophiesReads 13 of these genesDPM3DAG1FKRPPOMT1COL12A1COL6A1About this report →
Show 68 more reports
- Congenital Myasthenic SyndromeReads 12 of these genesPREPLCOL13A1COLQGFPT1MUSKSCN4AAbout this report →
- Dilated CardiomyopathyReads 12 of these genesDMDLMNAEMDFHL1MYPNSGCAAbout this report →
- Distal MyopathiesReads 7 of these genesHNRNPA1HNRNPA2B1VCPANO5TTNMYH7About this report →
- VitreoretinopathyReads 6 of these genesCOL2A1DYNC1H1LRP5COL9A1COL9A2COL9A3About this report →
- Spinal Muscular AtrophyReads 6 of these genesBICD2DYNC1H1HSPB8SMN1ASAH1PLEKHG5About this report →
- Charcot-Marie-Tooth DiseaseReads 10 of these genesDYNC1H1HSPB8LMNAVCPTRPV4MORC2About this report →
- Myofibrillar MyopathiesReads 4 of these genesHSPB8RYR1TTNFLNCAbout this report →
- Inherited Neurodegenerative DisordersReads 20 of these genesBICD2DYNC1H1HSPB8TUBA4AHNRNPA1HNRNPA2B1About this report →
- Achondrogenesis panelReads 2 of these genesCOL2A1SLC26A2About this report →
- ACAN-Related Short StatureReads 1 of these genesACANAbout this report →
- ACBD5 DeficiencyReads 1 of these genesACBD5About this report →
- Desbuquois Dysplasia 1Reads 1 of these genesCANT1About this report →
- Dyssegmental Dysplasia, Silverman-Handmaker TypeReads 1 of these genesHSPG2About this report →
- Dystrophinopathies (Duchenne and Becker Muscular Dystrophy)Reads 1 of these genesDMDAbout this report →
- HypophosphatasiaReads 1 of these genesALPLAbout this report →
- Mucopolysaccharidosis Type IVA (Morquio A Syndrome)Reads 1 of these genesGALNSAbout this report →
- MYH2-Related MyopathyReads 1 of these genesMYH2About this report →
- NOG-Related Symphalangism Spectrum DisorderReads 1 of these genesNOGAbout this report →
- Primary Failure of Tooth EruptionReads 1 of these genesPTH1RAbout this report →
- Progressive Pseudorheumatoid DysplasiaReads 1 of these genesCCN6About this report →
- Schmid Metaphyseal ChondrodysplasiaReads 1 of these genesCOL10A1About this report →
- Schwartz-Jampel Syndrome Type 1Reads 1 of these genesHSPG2About this report →
- SCN4A-Related Congenital MyopathyReads 1 of these genesSCN4AAbout this report →
- Spondyloepiphyseal Dysplasia With Congenital Joint DislocationsReads 1 of these genesCHST3About this report →
- Spondyloepiphyseal Dysplasia, Kondo-Fu TypeReads 1 of these genesMBTPS1About this report →
- TRPV4-Related Skeletal DysplasiasReads 1 of these genesTRPV4About this report →
- Sclerosing Bone Dysplasias (High Bone Mass)Reads 2 of these genesLRP5TGFB1About this report →
- Hereditary Spastic ParaplegiaReads 7 of these genesAP4B1AP4E1AP4M1AP4S1DSTYKHACE1About this report →
- Frontotemporal DementiaReads 3 of these genesHNRNPA1HNRNPA2B1VCPAbout this report →
- Congenital Disorders of GlycosylationReads 8 of these genesDPM3DAG1FKRPPOMT1ALG14ALG2About this report →
- Rare Hereditary Peripheral NeuropathiesReads 12 of these genesBICD2DYNC1H1HSPB8LMNAVCPSMN1About this report →
- Amyotrophic Lateral Sclerosis (ALS)Reads 4 of these genesTUBA4AHNRNPA1VCPVAPBAbout this report →
- Hereditary Rickets (Hypophosphatemic and Vitamin D-Dependent)Reads 2 of these genesPHEXSLC34A3About this report →
- Hypercalcemia InfantileReads 1 of these genesSLC34A1About this report →
- Malignant Hyperthermia SusceptibilityReads 1 of these genesRYR1About this report →
- Otospondylomegaepiphyseal Dysplasia (OSMED)Reads 1 of these genesCOL2A1About this report →
- Ehlers-Danlos SyndromeReads 3 of these genesFKBP14COL12A1SLC39A13About this report →
- Marfan Like SyndromesReads 2 of these genesBGNTGFB2About this report →
- Familial Periodic ParalysisReads 1 of these genesSCN4AAbout this report →
- Immuno-Osseous DysplasiasReads 1 of these genesSMARCAL1About this report →
- Osteogenesis ImperfectaReads 3 of these genesANO5LRP5IFIH1About this report →
- Hypertrophic CardiomyopathyReads 4 of these genesTRIM63MYPNMYH7FLNCAbout this report →
- Multiple Synostoses Syndrome (FGF9)Reads 1 of these genesNOGAbout this report →
- Polycystic Liver Disease (1 and 2)Reads 1 of these genesLRP5About this report →
- Inflammatory Bowel Diseases (IBD)Reads 1 of these genesTGFB1About this report →
- Loeys-Dietz SyndromeReads 1 of these genesTGFB2About this report →
- Left Ventricular NoncompactionReads 1 of these genesMYH7About this report →
- Aicardi-Goutieres SyndromeReads 1 of these genesIFIH1About this report →
- Progressive Cardiac Conduction Disease & Sick Sinus SyndromeReads 1 of these genesLMNAAbout this report →
- Dystonia, Myotonia, Paroxysmal DyskinesiaReads 2 of these genesSCN4ACOL6A3About this report →
- Arrhythmogenic CardiomyopathyReads 1 of these genesTMEM43About this report →
- Congenital Anomalies of the Kidney and Urinary TractReads 1 of these genesDSTYKAbout this report →
- LipodystrophyReads 1 of these genesLMNAAbout this report →
- Type I InterferonopathiesReads 1 of these genesIFIH1About this report →
- Aortic AneurysmReads 1 of these genesTGFB2About this report →
- OsteopetrosisReads 1 of these genesLRP5About this report →
- Lysosomal Storage DiseaseReads 2 of these genesGALNSASAH1About this report →
- Complex Cortical Dysplasia and Frontoparietal PolymicrogyriaReads 1 of these genesDYNC1H1About this report →
- Cutis LaxaReads 1 of these genesLTBP4About this report →
- Bardet-Biedl and Alström SyndromesReads 1 of these genesTRIM32About this report →
- Intellectual DisabilityReads 3 of these genesDYNC1H1DEAF1POGZAbout this report →
- Nephrotic SyndromeReads 1 of these genesLAMB2About this report →
- Rare Monogenic Autoinflammatory DiseasesReads 1 of these genesIFIH1About this report →
- Epilepsy (Full Panel)Reads 2 of these genesUFSP2HACE1About this report →
- Female InfertilityReads 1 of these genesTUBA4AAbout this report →
- Other Inborn Errors of ImmunityReads 2 of these genesIFIH1SMARCAL1About this report →
- Autosomal Recessive Cerebellar Ataxias (incl. CANVAS and AVED)Reads 1 of these genesSYNE1About this report →
- Other Inherited LeukodystrophiesReads 1 of these genesIFIH1About this report →
Leggi i geni collegati a Waddling gait e il resto del tuo genoma con un unico test.
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Ottieni il mio Genome Test129 geni collegati a Waddling gait
Alterazioni in questi geni causano malattie rare in cui si osserva Waddling gait. La maggior parte delle persone con questo tratto non presenta nessuna di tali condizioni, e un gene di questo elenco non dice nulla sul genoma di nessuno in particolare.
| Gene | Frequenza di osservazione | Condizioni |
|---|---|---|
| ACBD5acyl-CoA binding domain containing 5 | Sempre | In 1 condizione |
| BGNbiglycan | Sempre | In 1 condizione |
| BICD2BICD cargo adaptor 2 | Sempre | In 2 condizioni |
| CCN2cellular communication network factor 2 | Sempre | In 1 condizione |
| COL10A1collagen type X alpha 1 chain | Sempre | In 2 condizioni |
| COL2A1collagen type II alpha 1 chain | Sempre | In 5 condizioni |
| DMDdystrophin | Sempre | In 2 condizioni |
| DPM3dolichyl-phosphate mannosyltransferase subunit 3, regulatory | Sempre | In 1 condizione |
| DYMdymeclin | Sempre | In 2 condizioni |
| DYNC1H1dynein cytoplasmic 1 heavy chain 1 | Sempre | In 2 condizioni |
| FDX2ferredoxin 2 | Sempre | In 1 condizione |
| FEM1Bfem-1 homolog B | Sempre | In 1 condizione |
| FKBP14FKBP prolyl isomerase 14 | Sempre | In 1 condizione |
| GALNSgalactosamine (N-acetyl)-6-sulfatase | Sempre | In 1 condizione |
| HACD13-hydroxyacyl-CoA dehydratase 1 | Sempre | In 1 condizione |
| HSPB8heat shock protein family B (small) member 8 | Sempre | In 1 condizione |
| LMNAlamin A/C | Sempre | In 3 condizioni |
| MBTPS1membrane bound transcription factor peptidase, site 1 | Sempre | In 1 condizione |
| MYH2myosin heavy chain 2 | Sempre | In 1 condizione |
| PHEXphosphate regulating endopeptidase X-linked | Sempre | In 1 condizione |
| PREPLprolyl endopeptidase like | Sempre | In 1 condizione |
| TRIM63tripartite motif containing 63 | Sempre | In 1 condizione |
| TUBA4Atubulin alpha 4a | Sempre | In 1 condizione |
| UFSP2UFM1 specific peptidase 2 | Sempre | In 1 condizione |
| ACTA1actin alpha 1, skeletal muscle | Molto spesso (80–99%) | In 5 condizioni |
| CCN6cellular communication network factor 6 | Molto spesso (80–99%) | In 2 condizioni |
| CHST3carbohydrate sulfotransferase 3 | Molto spesso (80–99%) | In 2 condizioni |
| HNRNPA1heterogeneous nuclear ribonucleoprotein A1 | Molto spesso (80–99%) | In 1 condizione |
| HNRNPA2B1heterogeneous nuclear ribonucleoprotein A2/B1 | Molto spesso (80–99%) | In 1 condizione |
| LTBP4latent transforming growth factor beta binding protein 4 | Molto spesso (80–99%) | In 1 condizione |
| MATN3matrilin 3 | Molto spesso (80–99%) | In 2 condizioni |
| TRIM32tripartite motif containing 32 | Molto spesso (80–99%) | In 2 condizioni |
| VCPvalosin containing protein | Molto spesso (80–99%) | In 1 condizione |
| ANO5anoctamin 5 | Spesso (30–79%) | In 1 condizione |
| AP4B1adaptor related protein complex 4 subunit beta 1 | Spesso (30–79%) | In 2 condizioni |
| AP4E1adaptor related protein complex 4 subunit epsilon 1 | Spesso (30–79%) | In 1 condizione |
| AP4M1adaptor related protein complex 4 subunit mu 1 | Spesso (30–79%) | In 1 condizione |
| AP4S1adaptor related protein complex 4 subunit sigma 1 | Spesso (30–79%) | In 1 condizione |
| ARHGAP19Rho GTPase activating protein 19 | Spesso (30–79%) | In 1 condizione |
| BIN1bridging integrator 1 | Spesso (30–79%) | In 2 condizioni |
Mostra altri 89 geni
| Gene | Frequenza di osservazione | Condizioni |
|---|---|---|
| CFL2cofilin 2 | Spesso (30–79%) | In 2 condizioni |
| COL13A1collagen type XIII alpha 1 chain | Spesso (30–79%) | In 1 condizione |
| COLQcollagen like tail subunit of asymmetric acetylcholinesterase | Spesso (30–79%) | In 1 condizione |
| COMPcartilage oligomeric matrix protein | Spesso (30–79%) | In 4 condizioni |
| DAG1dystroglycan 1 | Spesso (30–79%) | In 1 condizione |
| DNAJB6DnaJ heat shock protein family (Hsp40) member B6 | Spesso (30–79%) | In 1 condizione |
| DSTYKdual serine/threonine and tyrosine protein kinase | Spesso (30–79%) | In 1 condizione |
| EMDemerin | Spesso (30–79%) | In 2 condizioni |
| FHL1four and a half LIM domains 1 | Spesso (30–79%) | In 3 condizioni |
| FKRPfukutin related protein | Spesso (30–79%) | In 2 condizioni |
| GFPT1glutamine--fructose-6-phosphate transaminase 1 | Spesso (30–79%) | In 2 condizioni |
| HACE1HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 | Spesso (30–79%) | In 2 condizioni |
| HSPG2heparan sulfate proteoglycan 2 | Spesso (30–79%) | In 1 condizione |
| LAMB2laminin subunit beta 2 | Spesso (30–79%) | In 1 condizione |
| LRP5LDL receptor related protein 5 | Spesso (30–79%) | In 1 condizione |
| MUSKmuscle associated receptor tyrosine kinase | Spesso (30–79%) | In 1 condizione |
| MYPNmyopalladin | Spesso (30–79%) | In 2 condizioni |
| POMT1protein O-mannosyltransferase 1 | Spesso (30–79%) | In 1 condizione |
| PTH1Rparathyroid hormone 1 receptor | Spesso (30–79%) | In 2 condizioni |
| RYR1ryanodine receptor 1 | Spesso (30–79%) | In 1 condizione |
| SCN4Asodium voltage-gated channel alpha subunit 4 | Spesso (30–79%) | In 2 condizioni |
| SGCAsarcoglycan alpha | Spesso (30–79%) | In 1 condizione |
| SGCBsarcoglycan beta | Spesso (30–79%) | In 1 condizione |
| SGCGsarcoglycan gamma | Spesso (30–79%) | In 1 condizione |
| SLC26A2solute carrier family 26 member 2 | Spesso (30–79%) | In 1 condizione |
| SLC6A17solute carrier family 6 member 17 | Spesso (30–79%) | In 2 condizioni |
| SMN1survival of motor neuron 1, telomeric | Spesso (30–79%) | In 1 condizione |
| SPEGstriated muscle enriched protein kinase | Spesso (30–79%) | In 1 condizione |
| SYNE1spectrin repeat containing nuclear envelope protein 1 | Spesso (30–79%) | In 1 condizione |
| SYNE2spectrin repeat containing nuclear envelope protein 2 | Spesso (30–79%) | In 1 condizione |
| SYT2synaptotagmin 2 | Spesso (30–79%) | In 1 condizione |
| TGFB1transforming growth factor beta 1 | Spesso (30–79%) | In 2 condizioni |
| TMEM43transmembrane protein 43 | Spesso (30–79%) | In 1 condizione |
| TNNC2troponin C2, fast skeletal type | Spesso (30–79%) | In 1 condizione |
| TNNT1troponin T1, slow skeletal type | Spesso (30–79%) | In 1 condizione |
| TRAPPC10trafficking protein particle complex subunit 10 | Spesso (30–79%) | In 1 condizione |
| TRAPPC11trafficking protein particle complex subunit 11 | Spesso (30–79%) | In 2 condizioni |
| TRPV4transient receptor potential cation channel subfamily V member 4 | Spesso (30–79%) | In 2 condizioni |
| TTNtitin | Spesso (30–79%) | In 1 condizione |
| ALG14ALG14 UDP-N-acetylglucosaminyltransferase subunit | A volte (5–29%) | In 1 condizione |
| ALG2ALG2 alpha-1,3/1,6-mannosyltransferase | A volte (5–29%) | In 2 condizioni |
| ASAH1N-acylsphingosine amidohydrolase 1 | A volte (5–29%) | In 1 condizione |
| COL12A1collagen type XII alpha 1 chain | A volte (5–29%) | In 1 condizione |
| COL6A1collagen type VI alpha 1 chain | A volte (5–29%) | In 1 condizione |
| COL6A2collagen type VI alpha 2 chain | A volte (5–29%) | In 1 condizione |
| COL6A3collagen type VI alpha 3 chain | A volte (5–29%) | In 1 condizione |
| COL9A1collagen type IX alpha 1 chain | A volte (5–29%) | In 1 condizione |
| COL9A2collagen type IX alpha 2 chain | A volte (5–29%) | In 2 condizioni |
| COL9A3collagen type IX alpha 3 chain | A volte (5–29%) | In 1 condizione |
| DEAF1DEAF1 transcription factor | A volte (5–29%) | In 1 condizione |
| DPAGT1dolichyl-phosphate N-acetylglucosaminephosphotransferase 1 | A volte (5–29%) | In 1 condizione |
| GMPPBGDP-mannose pyrophosphorylase B | A volte (5–29%) | In 1 condizione |
| IDH1isocitrate dehydrogenase (NADP(+)) 1 | A volte (5–29%) | In 1 condizione |
| KBTBD13kelch repeat and BTB domain containing 13 | A volte (5–29%) | In 1 condizione |
| KLHL41kelch like family member 41 | A volte (5–29%) | In 2 condizioni |
| LAMA2laminin subunit alpha 2 | A volte (5–29%) | In 1 condizione |
| LMOD3leiomodin 3 | A volte (5–29%) | In 1 condizione |
| MAP3K20mitogen-activated protein kinase kinase kinase 20 | A volte (5–29%) | In 1 condizione |
| MYH7myosin heavy chain 7 | A volte (5–29%) | In 1 condizione |
| NEBnebulin | A volte (5–29%) | In 3 condizioni |
| NOGnoggin | A volte (5–29%) | In 1 condizione |
| POGZpogo transposable element derived with ZNF domain | A volte (5–29%) | In 1 condizione |
| SELENONselenoprotein N | A volte (5–29%) | In 1 condizione |
| SLC34A1solute carrier family 34 member 1 | A volte (5–29%) | In 1 condizione |
| SLC34A3solute carrier family 34 member 3 | A volte (5–29%) | In 1 condizione |
| SPG7SPG7 matrix AAA peptidase subunit, paraplegin | A volte (5–29%) | In 1 condizione |
| TPM2tropomyosin 2 | A volte (5–29%) | In 3 condizioni |
| TPM3tropomyosin 3 | A volte (5–29%) | In 1 condizione |
| TTI1TELO2 interacting protein 1 | A volte (5–29%) | In 1 condizione |
| VAPBVAMP associated protein B and C | A volte (5–29%) | In 1 condizione |
| YY1YY1 transcription factor | A volte (5–29%) | In 2 condizioni |
| MORC2MORC family CW-type zinc finger 2 | Raramente (1–4%) | In 1 condizione |
| ACANaggrecan | Non registrato | In 1 condizione |
| ALPLalkaline phosphatase, biomineralization associated | Non registrato | In 1 condizione |
| CANT1calcium activated nucleotidase 1 | Non registrato | In 1 condizione |
| CHKBcholine kinase beta | Non registrato | In 1 condizione |
| DOK7docking protein 7 | Non registrato | In 1 condizione |
| FGD4FYVE, RhoGEF and PH domain containing 4 | Non registrato | In 1 condizione |
| FLNCfilamin C | Non registrato | In 1 condizione |
| FN1fibronectin 1 | Non registrato | In 1 condizione |
| IFIH1interferon induced with helicase C domain 1 | Non registrato | In 1 condizione |
| MMP13matrix metallopeptidase 13 | Non registrato | In 2 condizioni |
| NEFHneurofilament heavy chain | Non registrato | In 1 condizione |
| NEFLneurofilament light chain | Non registrato | In 1 condizione |
| PLEKHG5pleckstrin homology and RhoGEF domain containing G5 | Non registrato | In 1 condizione |
| POC1APOC1 centriolar protein A | Non registrato | In 1 condizione |
| SLC39A13solute carrier family 39 member 13 | Non registrato | In 1 condizione |
| SMARCAL1SNF2 related chromatin remodeling annealing helicase 1 | Non registrato | In 1 condizione |
| TGFB2transforming growth factor beta 2 | Non registrato | In 1 condizione |
Con quale frequenza questo tratto si presenta tra le persone con una delle condizioni legate al gene, nella misura più alta riscontrata tra queste, secondo quanto registrato dall'Human Phenotype Ontology. Queste pagine descrivono tratti e la ricerca che li riguarda; non costituiscono una diagnosi, e per i sintomi il medico o il consulente genetico è la persona a cui rivolgersi.
Tratti più generali
Fonte dei dati
- Human Phenotype Ontology, versione 2026-09-01: il tratto, i suoi nomi, la sua definizione e i geni a esso collegati. Per saperne di più visiti hpo.jax.org.
- Versione dei dati 2026.10.19-9814e911.
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