Trait
Cor pulmonale
Right-sided heart failure resulting from chronic hypertension in the pulmonary arteries and right ventricle.
Summary
- Body system
- Abnormality of the cardiovascular system
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
Read the genes linked to Cor pulmonale, and the rest of your genome, with one test.
From $449Free shipping · Results in 6–8 weeks
Get my Genome Test15 genes linked to Cor pulmonale
Changes in these genes cause rare conditions in which Cor pulmonale is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| ACTA1actin alpha 1, skeletal muscle | Sometimes (5–29%) | In 1 condition |
| CFTRCF transmembrane conductance regulator | Sometimes (5–29%) | In 1 condition |
| FCGR2AFc gamma receptor IIa | Sometimes (5–29%) | In 1 condition |
| HACD13-hydroxyacyl-CoA dehydratase 1 | Sometimes (5–29%) | In 1 condition |
| ITGA7integrin subunit alpha 7 | Sometimes (5–29%) | In 1 condition |
| MAP3K20mitogen-activated protein kinase kinase kinase 20 | Sometimes (5–29%) | In 1 condition |
| MYL2myosin light chain 2 | Sometimes (5–29%) | In 1 condition |
| SELENONselenoprotein N | Sometimes (5–29%) | In 1 condition |
| SOX9SRY-box transcription factor 9 | Sometimes (5–29%) | In 1 condition |
| TGFB1transforming growth factor beta 1 | Sometimes (5–29%) | In 1 condition |
| TPM2tropomyosin 2 | Sometimes (5–29%) | In 1 condition |
| TPM3tropomyosin 3 | Sometimes (5–29%) | In 1 condition |
| BTKBruton tyrosine kinase | Not recorded | In 1 condition |
| FLNAfilamin A | Not recorded | In 1 condition |
| SREBF1sterol regulatory element binding transcription factor 1 | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
One test. A lifetime of answers.
From $449Free shipping · Results in 6–8 weeks