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Trait

Persistent EBV viremia

Persistent or recurrent detection of Epstein-Barr virus (EBV) in the blood that occurs in the context of unusual susceptibility to infection.

HPO HP:0020072

Summary

Also called
Chronic EBV viremia, Persistent EBV viraemia, Recurrent EBV viremia
Body system
Laboratory abnormalityAbnormality of the immune system

19 genes linked to Persistent EBV viremia

Changes in these genes cause rare conditions in which Persistent EBV viremia is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.

GeneHow often it is seenConditions
CD28CD28 moleculeAlwaysIn 1 condition
IRF4interferon regulatory factor 4AlwaysIn 1 condition
ITKIL2 inducible T cell kinaseAlwaysIn 1 condition
ITPR3inositol 1,4,5-trisphosphate receptor type 3AlwaysIn 1 condition
MAGT1magnesium transporter 1AlwaysIn 1 condition
PRKCDprotein kinase C deltaAlwaysIn 1 condition
TNFRSF9TNF receptor superfamily member 9AlwaysIn 1 condition
CD27CD27 moleculeOften (30–79%)In 1 condition
DEF6DEF6 guanine nucleotide exchange factorOften (30–79%)In 1 condition
FLT3LGfms related receptor tyrosine kinase 3 ligandOften (30–79%)In 1 condition
IKZF3IKAROS family zinc finger 3Often (30–79%)In 1 condition
IL27RAinterleukin 27 receptor subunit alphaOften (30–79%)In 1 condition
LATlinker for activation of T cellsOften (30–79%)In 1 condition
PGM3phosphoglucomutase 3Often (30–79%)In 1 condition
STK4serine/threonine kinase 4Often (30–79%)In 1 condition
TET2tet methylcytosine dioxygenase 2Often (30–79%)In 1 condition
TOM1target of myb1 membrane trafficking proteinOften (30–79%)In 1 condition
TRACT cell receptor alpha constantOften (30–79%)In 1 condition
PIK3R1phosphoinositide-3-kinase regulatory subunit 1Sometimes (5–29%)In 1 condition

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Broader traits

Persistent viremiaUnusual EBV infection

Where this comes from

  • The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

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