Trait
Wide long bones of hand
Clinical name: Broad metacarpals
Abnormally broad metacarpal bones.
Summary
- Also called
- Wide metacarpals
Reference genomeGRCh38hg38
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Get my Genome Test18 genes linked to Wide long bones of hand
Changes in these genes cause rare conditions in which Wide long bones of hand is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| IFT140intraflagellar transport 140 | Always | In 1 condition |
| MMP2matrix metallopeptidase 2 | Always | In 2 conditions |
| PDE4Dphosphodiesterase 4D | Very often (80–99%) | In 1 condition |
| EXTL3exostosin like glycosyltransferase 3 | Often (30–79%) | In 1 condition |
| MMP14matrix metallopeptidase 14 | Often (30–79%) | In 1 condition |
| SLC26A2solute carrier family 26 member 2 | Often (30–79%) | In 1 condition |
| TFE3transcription factor binding to IGHM enhancer 3 | Often (30–79%) | In 1 condition |
| BMPR1Bbone morphogenetic protein receptor type 1B | Sometimes (5–29%) | In 1 condition |
| GDF5growth differentiation factor 5 | Sometimes (5–29%) | In 1 condition |
| GLB1galactosidase beta 1 | Sometimes (5–29%) | In 1 condition |
| IHHIndian hedgehog signaling molecule | Sometimes (5–29%) | In 1 condition |
| ADAMTS10ADAM metallopeptidase with thrombospondin type 1 motif 10 | Not recorded | In 1 condition |
| BGNbiglycan | Not recorded | In 1 condition |
| DDR2discoidin domain receptor tyrosine kinase 2 | Not recorded | In 1 condition |
| DNMT3ADNA methyltransferase 3 alpha | Not recorded | In 1 condition |
| FBN1fibrillin 1 | Not recorded | In 1 condition |
| FGFR1fibroblast growth factor receptor 1 | Not recorded | In 1 condition |
| NPR2natriuretic peptide receptor 2 | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
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Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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