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Gene

MMP14

matrix metallopeptidase 14

Summary

Cytogenetic location
14q11.2
Coordinates
Chromosome 14: 22,836,585–22,847,758 (GRCh38)
Exons
10 exons across 11.2 kb
Protein
582 amino acids
Also known as
MT1-MMP
MANE Select transcript
ENST00000311852.11NM_004995.4
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads MMP14 yet. The test sequences your whole genome, so your data includes it all the same.

How MMP14 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 14, with a bracket where MMP14 sits. MMP14 and 28 genes near it on chromosome 14, from 22,342,172 to 23,342,171.Chromosome 1414q11.2p13p12p11.2p11.1q11.1q11.2q12q13.1q13.2q13.3q21.1q21.2q21.3q22.1q22.2q22.3q23.1q23.2q23.3q24.1q24.2q24.3q31.1q31.2q31.3q32.11q32.12q32.13q32.2q32.31q32.32q32.3322.4 Mb22.6 Mb22.8 Mb23 Mb23.2 MbDAD1: 22,564,902–22,589,245, reverse strandDAD1ABHD4: 22,598,243–22,612,963, forward strandABHD4OR6J1: 22,630,929–22,644,352, reverse strandOR6J1OXA1L: 22,766,522–22,776,355, forward strandOXA1LSLC7A7: 22,773,222–22,829,820, reverse strandSLC7A7MRPL52: 22,829,871–22,836,024, forward strandMRPL52MMP14: 22,836,585–22,847,758, forward strandMMP14LRP10: 22,871,709–22,881,713, forward strandLRP10REM2: 22,883,136–22,887,686, forward strandREM2RBM23: 22,893,204–22,919,182, reverse strandRBM23PRMT5: 22,920,108–22,929,458, reverse strandPRMT5HAUS4: 22,946,228–22,957,161, reverse strandHAUS4: 22,946,270–22,982,258, reverse strandAJUBA: 22,971,177–22,982,647, reverse strandAJUBAC14orf93: 22,985,894–23,010,529, reverse strandC14orf93PSMB5: 23,016,540–23,035,239, reverse strandPSMB5PSMB11: 23,042,212–23,044,060, forward strandPSMB11CDH24: 23,047,062–23,057,668, reverse strandCDH24ACIN1: 23,058,561–23,095,614, reverse strandACIN1C14orf119: 23,094,692–23,100,456, forward strandC14orf119CIROP: 23,099,062–23,105,018, reverse strandCIROPCEBPE: 23,117,036–23,120,256, reverse strandCEBPESLC7A8: 23,125,295–23,183,683, reverse strandSLC7A8RNF212B: 23,185,316–23,273,477, forward strandRNF212BHOMEZ: 23,258,697–23,299,796, reverse strandHOMEZPPP1R3E: 23,295,652–23,302,950, reverse strandPPP1R3EBCL2L2: 23,298,790–23,313,069, forward strandBCL2L2BCL2L2-PABPN1: 23,306,833–23,326,175, forward strandPABPN1: 23,321,447–23,326,176, forward strandDiagram of MMP14: 10 exons on the forward strand of chromosome 14Exon 1: 22,836,585–22,836,925, 341 basesExon 2: 22,841,491–22,841,639, 149 basesExon 3: 22,841,913–22,842,035, 123 basesExon 4: 22,842,410–22,842,717, 308 basesExon 5: 22,843,257–22,843,418, 162 basesExon 6: 22,843,710–22,843,870, 161 basesExon 7: 22,844,371–22,844,509, 139 basesExon 8: 22,844,630–22,844,780, 151 basesExon 9: 22,845,251–22,845,366, 116 basesExon 10: 22,845,708–22,847,758, 2,051 bases123456789105′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 3.7 kb of the gene's 11.2 kb; 1,749 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.

Cite this page

APA

Dante Labs. (n.d.). MMP14 gene: matrix metallopeptidase 14. Retrieved 16 October 2026, from https://dantelabs.com/genes/mmp14

Vancouver

Dante Labs. MMP14 gene: matrix metallopeptidase 14 [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/mmp14

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