Gene
YME1L1
YME1 like 1 ATPase
- HGNC 12843↗(opens in a new tab)
- Ensembl gene ENSG00000136758↗(opens in a new tab)
- NCBI Gene 10730↗(opens in a new tab)
Summary
- Cytogenetic location
- 10p12.1
- Coordinates
- Chromosome 10: 27,110,111–27,154,384 (GRCh38)
- Exons
- 19 exons across 44.3 kb
- Protein
- 716 amino acids
- Also known as
- YME1L
- MANE Select transcript
- ENST00000376016.8NM_014263.4
- Locus type
- gene with protein product
- Very high
- Confident
- Low
- Very low
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
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How YME1L1 is laid out
- Coding sequence
- Untranslated region
- Intron
- Direction of transcription
- Stretches short reads find hard
Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.
Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).
Nearby genes from Ensembl release 116, on GRCh38.
Exons make up 4.2 kb of the gene's 44.3 kb; 2,151 of those bases code for the protein.
Traits linked to YME1L1
The Human Phenotype Ontology lists these as features of the rare conditions YME1L1 can cause. Each trait's page lists the other genes linked to it.
Abnormality of the nervous system
- Communication delay
- Global developmental delay
- Intellectual disability
- Leukoencephalopathy
- Motor delay
- Ataxia
- Decreased sensory nerve conduction velocity
- EEG with focal sharp waves
Show 15 more traits
- Incomprehensible speech
- Lack of coordination of movement
- Poor speech
- Small cerebellum
- Absent speech development
- Attention deficit
- Brain degeneration
- Delayed CNS myelination
- Epilepsy
- Gait apraxia
- Hyperactive movements
- Involuntary writhing movements in fingers, hands, toes, and feet
- More active than typical
- Stereotypical body rocking
- Ventriculomegaly
External links
Gene records
Transcript
Protein
Where this comes from
- HGNC: the gene's symbol, name, other symbols and location.
- MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
- The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
Cite this page
Dante Labs. (n.d.). YME1L1 gene: YME1 like 1 ATPase. Retrieved 17 October 2026, from https://dantelabs.com/genes/yme1l1
Dante Labs. YME1L1 gene: YME1 like 1 ATPase [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/yme1l1
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