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Gene

VWA8

von Willebrand factor A domain containing 8

Summary

Cytogenetic location
13q14.11
Coordinates
Chromosome 13: 41,566,835–41,961,109 (GRCh38)
Exons
45 exons across 394.3 kb
Protein
1,905 amino acids
Also known as
P7BP2
Previous symbols
KIAA0564
MANE Select transcript
ENST00000379310.8NM_015058.2
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated report relevant to this gene

    • Retinitis Pigmentosa

      • One of 77 genes linked to it

        A group of inherited retinal dystrophies with progressive loss of rod and then cone photoreceptors, causing night blindness and gradual loss of peripheral vision.

        • 1 GenCC submitter rates it definitive or strong

    How VWA8 is laid out

    • Coding sequence
    • Untranslated region
    • Intron
    • Direction of transcription
    • Stretches short reads find hard
    Chromosome 13, with a bracket where VWA8 sits. VWA8 and 6 genes near it on chromosome 13, from 41,172,560 to 42,355,384.Chromosome 1313q14.11p13p12p11.2p11.1q11q12.11q12.12q12.13q12.2q12.3q13.1q13.2q13.3q14.11q14.12q14.13q14.2q14.3q21.1q21.2q21.31q21.32q21.33q22.1q22.2q22.3q31.1q31.2q31.3q32.1q32.2q32.3q33.1q33.2q33.3q3441.2 Mb41.4 Mb41.6 Mb41.8 Mb42 Mb42.2 MbKBTBD7: 41,189,834–41,194,569, reverse strandKBTBD7MTRF1: 41,216,145–41,311,831, reverse strandMTRF1NAA16: 41,311,225–41,377,161, forward strandNAA16RGCC: 41,456,949–41,470,883, forward strandRGCCVWA8: 41,566,835–41,961,109, reverse strandVWA8DGKH: 42,040,036–42,256,578, forward strandDGKHAKAP11: 42,271,470–42,323,283, forward strandAKAP11Diagram of VWA8: 45 exons on the reverse strand of chromosome 13Exon 45: 41,566,835–41,568,305, 1,471 basesExon 44: 41,570,468–41,570,706, 239 basesExon 43: 41,575,740–41,575,838, 99 basesExon 42: 41,587,512–41,587,670, 159 basesExon 41: 41,590,640–41,590,765, 126 basesExon 40: 41,605,168–41,605,276, 109 basesExon 39: 41,611,576–41,611,732, 157 basesExon 38: 41,614,976–41,615,084, 109 basesExon 37: 41,670,946–41,671,147, 202 basesExon 36: 41,675,215–41,675,296, 82 basesExon 35: 41,685,047–41,685,242, 196 basesExon 34: 41,689,354–41,689,508, 155 basesExon 33: 41,690,166–41,690,275, 110 basesExon 32: 41,691,320–41,691,445, 126 basesExon 31: 41,691,874–41,691,938, 65 basesExon 30: 41,692,862–41,692,972, 111 basesExon 29: 41,699,071–41,699,270, 200 basesExon 28: 41,701,392–41,701,530, 139 basesExon 27: 41,703,303–41,703,411, 109 basesExon 26: 41,719,591–41,719,742, 152 basesExon 25: 41,721,370–41,721,575, 206 basesExon 24: 41,727,194–41,727,313, 120 basesExon 23: 41,729,542–41,729,677, 136 basesExon 22: 41,732,080–41,732,155, 76 basesExon 21: 41,761,128–41,761,204, 77 basesExon 20: 41,777,985–41,778,056, 72 basesExon 19: 41,783,795–41,783,901, 107 basesExon 18: 41,787,437–41,787,543, 107 basesExon 17: 41,811,225–41,811,340, 116 basesExon 16: 41,816,698–41,816,775, 78 basesExon 15: 41,819,218–41,819,386, 169 basesExon 14: 41,830,529–41,830,642, 114 basesExon 13: 41,833,371–41,833,531, 161 basesExon 12: 41,865,736–41,865,813, 78 basesExon 11: 41,865,902–41,866,036, 135 basesExon 10: 41,868,346–41,868,477, 132 basesExon 9: 41,883,387–41,883,491, 105 basesExon 8: 41,885,920–41,886,028, 109 basesExon 7: 41,886,781–41,886,830, 50 basesExon 6: 41,887,197–41,887,361, 165 basesExon 5: 41,891,420–41,891,587, 168 basesExon 4: 41,907,586–41,907,696, 111 basesExon 3: 41,912,038–41,912,168, 131 basesExon 2: 41,949,936–41,950,013, 78 basesExon 1: 41,960,853–41,961,109, 257 bases454030201015′3′

    Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

    Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

    Nearby genes from Ensembl release 116, on GRCh38.

    Exons make up 7.2 kb of the gene's 394.3 kb; 5,718 of those bases code for the protein.

    Where this comes from

    • HGNC: the gene's symbol, name, other symbols and location.
    • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
    • GenCC and ClinGen, released 2026-10-16: which conditions the gene is linked to, and how strongly.
    • The ACMG secondary findings list, SF v3.2.
    • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
    • Data release 2026.10.16-c6eea6bf.

    Cite this page

    APA

    Dante Labs. (n.d.). VWA8 gene: von Willebrand factor A domain containing 8. Retrieved 17 October 2026, from https://dantelabs.com/genes/vwa8

    Vancouver

    Dante Labs. VWA8 gene: von Willebrand factor A domain containing 8 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/vwa8

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