Traits

Traits linked to RAB32

RAB32, member RAS oncogene family

The Human Phenotype Ontology links 40 traits to RAB32, by body system: features seen in people with one of the gene's rare conditions.

Abnormality of the nervous system

Trait	How often it is seen
Akinesia	Always
Anxiety	Always
Clumsiness	Always
Dystonia	Always
Falls	Always
Freezing of gait	Always
Hand tremor	Always
Impulsivity	Always
Lethargy	Always
Micrographia	Always
Neurofibrillary tangles	Always
Parkinsonism	Always
Parkinsonism with favorable response to dopaminergic medication	Always
Peripheral nerve disease	Always
Pins and needles feeling	Always
Slow movements	Always
Subcortical cerebral atrophy	Always
Substantia nigra dopaminergic neuron loss	Always
Suicide behaviors	Always
Tremor	Always
Balance impairment	Often (30–79%)
Cognitive impairment	Often (30–79%)
Depression	Often (30–79%)
Disorder of involuntary muscle movements	Often (30–79%)
Hallucinations	Often (30–79%)
REM sleep behavior disorder	Often (30–79%)
Resting tremor	Often (30–79%)

Abnormality of the musculoskeletal system

Trait	How often it is seen
Back pain	Always
Camptocormia	Always
Rigidity	Always
Upper limb pain	Always

Abnormality of the digestive system

Trait	How often it is seen
Constipation	Always
Poor swallowing	Always
Stomach ulcer	Always

Abnormality of the cardiovascular system

Trait	How often it is seen
High blood pressure	Always
Low blood pressure	Always

Abnormal tissue mass

Trait	How often it is seen
Abnormal tissue mass	Always

Abnormality of head or neck

Trait	How often it is seen
Hyposmia	Very often (80–99%)

Abnormality of the genitourinary system

Trait	How often it is seen
Urinary urgency	Always

Abnormality of the immune system

Trait	How often it is seen
Aspiration pneumonia	Always

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Where this comes from

The Human Phenotype Ontology, release 2026-09-01: the traits linked to RAB32 and how often each is seen. Find out more at hpo.jax.org.

One test. A lifetime of answers.

From $449Free shipping · Results in 6–8 weeks

Get my Genome Test