Traits

Traits linked to RAB11B

RAB11B, member RAS oncogene family

The Human Phenotype Ontology links 41 traits to RAB11B, by body system: features seen in people with one of the gene's rare conditions.

Abnormality of the nervous system

Trait	How often it is seen
Abnormal gait	Always
Absent speech development	Always
Cerebellar vermis hypoplasia	Always
Delayed ability to walk	Always
Delayed motor skills	Always
Global developmental delay	Always
Intellectual disability	Always
Reduced cerebral white matter volume	Always
Small brainstem	Always
Thin corpus callosum	Always
Ventriculomegaly	Always
Wide based walk	Always
Dystonia	Often (30–79%)
Generalized-onset seizure	Often (30–79%)
Inability to coordinate movements when walking	Often (30–79%)
Repetitive movements	Often (30–79%)
Delayed CNS myelination	Sometimes (5–29%)
Happy demeanor	Sometimes (5–29%)
Obstructive sleep apnea	Sometimes (5–29%)
Poor eye contact	Sometimes (5–29%)

Abnormality of limbs

Trait	How often it is seen
Tapered finger	Always
Single transverse palmar crease	Often (30–79%)
Club foot on both sides	Sometimes (5–29%)
Curvature of little finger	Sometimes (5–29%)
High-arched foot	Sometimes (5–29%)
Overlapping toe	Sometimes (5–29%)

Abnormality of head or neck

Trait	How often it is seen
Abnormally small head	Very often (80–99%)
Decreased facial muscle tone	Sometimes (5–29%)
Drooling	Sometimes (5–29%)
Tented mouth	Sometimes (5–29%)
Upward slanting of the opening between the eyelids	Sometimes (5–29%)

Abnormality of the eye

Trait	How often it is seen
Cross-eyed	Often (30–79%)
Farsightedness	Often (30–79%)
Involuntary, rapid, rhythmic eye movements	Often (30–79%)
Optic atrophy	Sometimes (5–29%)
Visual impairment	Sometimes (5–29%)

Abnormality of the musculoskeletal system

Trait	How often it is seen
Abnormal formation of the hip	Very often (80–99%)
Low muscle tone	Very often (80–99%)
Involuntary muscle stiffness, contraction, or spasm	Often (30–79%)

Abnormality of the digestive system

Trait	How often it is seen
Feeding difficulties	Sometimes (5–29%)

Abnormality of the ear

Trait	How often it is seen
Prominent antihelix	Sometimes (5–29%)

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Where this comes from

The Human Phenotype Ontology, release 2026-09-01: the traits linked to RAB11B and how often each is seen. Find out more at hpo.jax.org.

One test. A lifetime of answers.

From $449Free shipping · Results in 6–8 weeks

Get my Genome Test