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Gene

RAB11B

RAB11B, member RAS oncogene family

Summary

Cytogenetic location
19p13.2
Coordinates
Chromosome 19: 8,390,360–8,404,434 (GRCh38)
Exons
5 exons across 14.1 kb
Protein
218 amino acids
Also known as
H-YPT3
MANE Select transcript
ENST00000328024.11NM_004218.4
Locus type
Protein-coding
  • Very high
  • Confident
  • Low
  • Very low

Curated reports relevant to this gene

No Genome Test report reads RAB11B yet. The test sequences your whole genome, so your data includes it all the same.

How RAB11B is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 19, with a bracket where RAB11B sits. RAB11B and 28 genes near it on chromosome 19, from 7,897,397 to 8,897,396.Chromosome 1919p13.2p13.3p13.2p13.13p13.12p13.11p12p11q11q12q13.11q13.12q13.13q13.2q13.31q13.32q13.33q13.41q13.42q13.438 Mb8.2 Mb8.4 Mb8.6 Mb8.8 MbLRRC8E: 7,888,500–7,902,021, forward strandMAP2K7: 7,903,823–7,914,480, forward strandTGFBR3L: 7,914,760–7,919,097, forward strandTGFBR3LSNAPC2: 7,920,314–7,923,250, forward strandSNAPC2CTXN1: 7,924,491–7,926,174, reverse strandCTXN1TIMM44: 7,926,715–7,943,773, reverse strandTIMM44ELAVL1: 7,958,573–8,006,062, reverse strandELAVL1CCL25: 8,052,293–8,062,665, forward strandCCL25FBN3: 8,065,402–8,149,693, reverse strandFBN3CERS4: 8,206,736–8,263,716, forward strandCERS4CD320: 8,302,123–8,308,379, reverse strandRPS28: 8,307,760–8,323,567, forward strandRPS28: 8,308,283–8,321,379, reverse strandNDUFA7: 8,308,593–8,321,400, reverse strandNDUFA7KANK3: 8,322,582–8,343,281, reverse strandKANK3ANGPTL4: 8,363,223–8,374,371, forward strandANGPTL4RAB11B: 8,390,360–8,404,434, forward strandRAB11BMARCHF2: 8,411,460–8,439,017, forward strandMARCHF2HNRNPM: 8,444,767–8,489,118, forward strandHNRNPMPRAM1: 8,490,056–8,502,656, reverse strandPRAM1ZNF414: 8,509,678–8,514,177, reverse strandZNF414MYO1F: 8,517,463–8,577,473, reverse strandMYO1FADAMTS10: 8,580,240–8,610,846, reverse strandADAMTS10NFILZ: 8,630,633–8,681,151, forward strandNFILZACTL9: 8,697,400–8,698,795, reverse strandACTL9OR2Z1: 8,721,634–8,732,160, forward strandOR2Z1ZNF558: 8,806,170–8,832,319, reverse strandZNF558MBD3L1: 8,832,365–8,843,340, forward strandMBD3L1MUC16: 8,848,638–9,010,438, reverse strandMUC16Diagram of RAB11B: 5 exons on the forward strand of chromosome 19Exon 2: 3 known disease-causing sitesExon 1: 8,390,360–8,390,456, 97 basesExon 2: 8,399,863–8,400,058, 196 basesExon 3: 8,402,086–8,402,279, 194 basesExon 4: 8,402,485–8,402,565, 81 basesExon 5: 8,403,413–8,404,434, 1,022 bases123455′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 1.6 kb of the gene's 14.1 kb; 657 of those bases code for the protein.

Sequencing RAB11B

8Low

How hard RAB11B is to sequence with short reads, out of 100

  • Mappability0%
  • Homology0%
  • Repeats6.7%
  • GC content74%
  • Reference coverage0%

3

positions in RAB11B where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 14.1 kb of RAB11B, introns included, not only the 1.6 kb of exons.

Traits linked to RAB11B

The Human Phenotype Ontology lists these as features of the rare conditions RAB11B can cause. Each trait's page lists the other genes linked to it.

External links

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Genome in a Bottle genome stratifications, from NIST: the sequencing difficulty score.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.17-8666dff2.

Cite this page

APA

Dante Labs. (n.d.). RAB11B gene: RAB11B, member RAS oncogene family. Retrieved 17 October 2026, from https://dantelabs.com/genes/rab11b

Vancouver

Dante Labs. RAB11B gene: RAB11B, member RAS oncogene family [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/rab11b

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