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Gene

HSD17B1

hydroxysteroid 17-beta dehydrogenase 1

Summary

Cytogenetic location
17q21.2
Coordinates
Chromosome 17: 42,552,923–42,555,214 (GRCh38)
Exons
6 exons across 2.3 kb
Protein
328 amino acids
Also known as
HSD17, MGC138140, SDR28C1
Previous symbols
EDHB17, EDH17B2
MANE Select transcript
ENST00000585807.6NM_000413.4
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads HSD17B1 yet. The test sequences your whole genome, so your data includes it all the same.

How HSD17B1 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 17, with a bracket where HSD17B1 sits. HSD17B1 and 44 genes near it on chromosome 17, from 42,054,069 to 43,054,068.Chromosome 1717q21.2p13.3p13.2p13.1p12p11.2p11.1q11.1q11.2q12q21.1q21.2q21.31q21.32q21.33q22q23.1q23.2q23.3q24.1q24.2q24.3q25.1q25.2q25.342.2 Mb42.4 Mb42.6 Mb42.8 Mb43 MbZNF385C: 42,025,576–42,098,479, reverse strandZNF385CDHX58: 42,101,404–42,112,735, reverse strandKAT2A: 42,113,109–42,121,382, reverse strand: 42,119,674–42,154,916, reverse strandHSPB9: 42,122,804–42,123,352, forward strandHSPB9RAB5C: 42,124,976–42,155,044, reverse strandRAB5CKCNH4: 42,156,891–42,181,146, reverse strandKCNH4HCRT: 42,184,060–42,185,452, reverse strandHCRTGHDC: 42,188,799–42,194,513, reverse strandGHDCSTAT5B: 42,199,176–42,288,633, reverse strandSTAT5BSTAT5A: 42,287,547–42,311,943, forward strandSTAT5ASTAT3: 42,313,322–42,388,574, reverse strandSTAT3CAVIN1: 42,402,449–42,423,322, reverse strandCAVIN1ATP6V0A1: 42,458,823–42,522,582, forward strandATP6V0A1NAGLU: 42,536,216–42,544,449, forward strandNAGLUHSD17B1: 42,552,923–42,555,214, forward strandHSD17B1COASY: 42,561,467–42,566,277, forward strandCOASYMLX: 42,567,067–42,573,239, forward strandMLXPSMC3IP: 42,572,310–42,577,831, reverse strandRETREG3: 42,579,508–42,610,623, reverse strandTUBG1: 42,609,411–42,615,253, forward strandTUBG2: 42,659,223–42,667,007, forward strandTUBG2PLEKHH3: 42,667,914–42,677,064, reverse strandPLEKHH3CCR10: 42,678,889–42,683,917, reverse strandCCR10CNTNAP1: 42,682,368–42,699,993, forward strandCNTNAP1EZH1: 42,700,270–42,745,069, reverse strandEZH1RAMP2: 42,758,447–42,763,537, forward strandRAMP2VPS25: 42,773,439–42,779,600, forward strandVPS25WNK4: 42,780,593–42,797,066, forward strandWNK4COA3: 42,793,154–42,798,719, reverse strandCOA3CNTD1: 42,798,800–42,811,587, forward strandBECN1: 42,809,108–42,833,350, reverse strandBECN1PSME3: 42,824,385–42,843,760, forward strandAOC2: 42,844,574–42,850,707, forward strandAOC2AOC3: 42,851,130–42,858,130, forward strandAOC3G6PC1: 42,900,722–42,923,502, forward strandG6PC1AARSD1: 42,950,424–42,964,498, reverse strandAARSD1PTGES3L-AARSD1: 42,950,526–42,980,528, reverse strandPTGES3L-AARSD1PTGES3L: 42,968,035–42,980,502, reverse strandPTGES3LRUNDC1: 42,980,552–42,995,142, forward strandRUNDC1RPL27: 42,998,265–43,002,973, forward strandVAT1: 42,999,182–43,025,123, reverse strandIFI35: 43,006,740–43,014,638, forward strandRND2: 43,025,210–43,047,509, forward strandBRCA1: 43,044,292–43,170,245, reverse strandBRCA1Diagram of HSD17B1: 6 exons on the forward strand of chromosome 17Exon 1: 42,552,923–42,553,030, 108 basesExon 2: 42,553,124–42,553,291, 168 basesExon 3: 42,553,439–42,553,618, 180 basesExon 4: 42,553,794–42,553,887, 94 basesExon 5: 42,554,405–42,554,582, 178 basesExon 6: 42,554,669–42,555,214, 546 bases1234565′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 1.3 kb of the gene's 2.3 kb; 987 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.

Cite this page

APA

Dante Labs. (n.d.). HSD17B1 gene: hydroxysteroid 17-beta dehydrogenase 1. Retrieved 17 October 2026, from https://dantelabs.com/genes/hsd17b1

Vancouver

Dante Labs. HSD17B1 gene: hydroxysteroid 17-beta dehydrogenase 1 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/hsd17b1

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