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Gene

LRRC8C

leucine rich repeat containing 8 VRAC subunit C

Summary

Cytogenetic location
1p22.2
Coordinates
Chromosome 1: 89,633,120–89,719,533 (GRCh38)
Exons
3 exons across 86.4 kb
Protein
803 amino acids
Also known as
AD158
MANE Select transcript
ENST00000370454.9NM_032270.5
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads LRRC8C yet. The test sequences your whole genome, so your data includes it all the same.

How LRRC8C is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 1, with a bracket where LRRC8C sits. LRRC8C and 8 genes near it on chromosome 1, from 89,176,327 to 90,176,326.Chromosome 11p22.2p36.33p36.32p36.31p36.23p36.22p36.21p36.13p36.12p36.11p35.3p35.2p35.1p34.3p34.2p34.1p33p32.3p32.2p32.1p31.3p31.2p31.1p22.3p22.2p22.1p21.3p21.2p21.1p13.3p13.2p13.1p12p11.2p11.1q11q12q21.1q21.2q21.3q22q23.1q23.2q23.3q24.1q24.2q24.3q25.1q25.2q25.3q31.1q31.2q31.3q32.1q32.2q32.3q41q42.11q42.12q42.13q42.2q42.3q43q4489.2 Mb89.4 Mb89.6 Mb89.8 Mb90 MbGBP4: 89,181,144–89,198,953, reverse strandGBP4GBP5: 89,256,189–89,272,892, reverse strandGBP5GBP6: 89,363,895–89,388,160, forward strandGBP6LRRC8B: 89,524,160–89,597,861, forward strandLRRC8B: 89,579,592–89,579,654, forward strandLRRC8C: 89,633,120–89,719,533, forward strandLRRC8C: 89,633,140–89,933,250, forward strandLRRC8D: 89,820,973–89,936,611, forward strandLRRC8DZNF326: 89,995,110–90,035,548, forward strandZNF326Diagram of LRRC8C: 3 exons on the forward strand of chromosome 1Exon 1: 89,633,120–89,633,322, 203 basesExon 2: 89,686,470–89,686,611, 142 basesExon 3: 89,712,709–89,719,533, 6,825 bases1235′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 7.2 kb of the gene's 86.4 kb; 2,412 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.

Cite this page

APA

Dante Labs. (n.d.). LRRC8C gene: leucine rich repeat containing 8 VRAC subunit C. Retrieved 17 October 2026, from https://dantelabs.com/genes/lrrc8c

Vancouver

Dante Labs. LRRC8C gene: leucine rich repeat containing 8 VRAC subunit C [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/lrrc8c

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