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Gene

LRRC8B

leucine rich repeat containing 8 VRAC subunit B

Summary

Cytogenetic location
1p22.2
Coordinates
Chromosome 1: 89,524,829–89,597,861 (GRCh38)
Exons
6 exons across 73 kb
Protein
803 amino acids
Also known as
TA-LRRP, KIAA0231
MANE Select transcript
ENST00000330947.7NM_001369817.2
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads LRRC8B yet. The test sequences your whole genome, so your data includes it all the same.

How LRRC8B is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 1, with a bracket where LRRC8B sits. LRRC8B and 11 genes near it on chromosome 1, from 89,061,345 to 90,061,344.Chromosome 11p22.2p36.33p36.32p36.31p36.23p36.22p36.21p36.13p36.12p36.11p35.3p35.2p35.1p34.3p34.2p34.1p33p32.3p32.2p32.1p31.3p31.2p31.1p22.3p22.2p22.1p21.3p21.2p21.1p13.3p13.2p13.1p12p11.2p11.1q11q12q21.1q21.2q21.3q22q23.1q23.2q23.3q24.1q24.2q24.3q25.1q25.2q25.3q31.1q31.2q31.3q32.1q32.2q32.3q41q42.11q42.12q42.13q42.2q42.3q43q4489.2 Mb89.4 Mb89.6 Mb89.8 Mb90 MbGBP1: 89,051,135–89,072,769, reverse strandGBP1GBP2: 89,106,132–89,150,456, reverse strandGBP2GBP7: 89,130,235–89,176,083, reverse strandGBP7GBP4: 89,181,144–89,198,953, reverse strandGBP4GBP5: 89,256,189–89,272,892, reverse strandGBP5GBP6: 89,363,895–89,388,160, forward strandGBP6LRRC8B: 89,524,829–89,597,861, forward strandLRRC8B: 89,579,592–89,579,654, forward strandLRRC8C: 89,632,693–89,769,903, forward strandLRRC8C: 89,633,140–89,933,250, forward strandLRRC8D: 89,820,973–89,936,611, forward strandLRRC8DZNF326: 89,995,110–90,035,548, forward strandZNF326Diagram of LRRC8B: 6 exons on the forward strand of chromosome 1Exon 1: 89,524,829–89,525,022, 194 basesExon 2: 89,568,247–89,568,307, 61 basesExon 3: 89,568,439–89,568,493, 55 basesExon 4: 89,579,591–89,579,688, 98 basesExon 5: 89,582,625–89,584,789, 2,165 basesExon 6: 89,592,771–89,597,861, 5,091 bases12465′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 7.7 kb of the gene's 73 kb; 2,412 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.

Cite this page

APA

Dante Labs. (n.d.). LRRC8B gene: leucine rich repeat containing 8 VRAC subunit B. Retrieved 17 October 2026, from https://dantelabs.com/genes/lrrc8b

Vancouver

Dante Labs. LRRC8B gene: leucine rich repeat containing 8 VRAC subunit B [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/lrrc8b

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