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Gene

PAK6

p21 (RAC1) activated kinase 6

Summary

Cytogenetic location
15q15.1
Coordinates
Chromosome 15: 40,239,063–40,277,487 (GRCh38)
Exons
11 exons across 38.4 kb
Protein
681 amino acids
Also known as
PAK5
MANE Select transcript
ENST00000560346.6NM_001395430.1
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads PAK6 yet. The test sequences your whole genome, so your data includes it all the same.

How PAK6 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 15, with a bracket where PAK6 sits. PAK6 and 22 genes near it on chromosome 15, from 39,758,275 to 40,758,274.Chromosome 1515q15.1p13p12p11.2p11.1q11.1q11.2q12q13.1q13.2q13.3q14q15.1q15.2q15.3q21.1q21.2q21.3q22.1q22.2q22.31q22.32q22.33q23q24.1q24.2q24.3q25.1q25.2q25.3q26.1q26.2q26.339.8 Mb40 Mb40.2 Mb40.4 Mb40.6 MbFSIP1: 39,588,357–39,782,858, reverse strandFSIP1GPR176: 39,799,003–39,920,976, reverse strandGPR176EIF2AK4: 39,934,062–40,036,656, forward strandEIF2AK4SRP14: 40,032,985–40,039,186, reverse strandSRP14BMF: 40,087,889–40,108,928, reverse strandBMFBUB1B: 40,160,984–40,221,137, forward strandBUB1BBUB1B-PAK6: 40,218,500–40,264,890, forward strandBUB1B-PAK6PAK6: 40,239,063–40,277,487, forward strandPAK6PLCB2: 40,278,176–40,307,965, reverse strandPLCB2ANKRD63: 40,278,372–40,283,064, reverse strandANKRD63INAFM2: 40,323,692–40,326,715, forward strandINAFM2CCDC9B: 40,331,452–40,340,954, reverse strandCCDC9BPHGR1: 40,351,025–40,357,622, forward strandPHGR1DISP2: 40,358,219–40,378,621, forward strandDISP2KNSTRN: 40,382,721–40,395,659, forward strandKNSTRNIVD: 40,405,485–40,435,956, forward strandIVDBAHD1: 40,436,611–40,468,242, forward strandBAHD1CHST14: 40,470,984–40,473,158, forward strandCHST14CCDC32: 40,519,519–40,565,054, reverse strandCCDC32RPUSD2: 40,569,289–40,575,171, forward strandRPUSD2KNL1: 40,594,002–40,664,342, forward strandKNL1RAD51: 40,694,774–40,732,344, forward strandRAD51RMDN3: 40,720,655–40,755,851, reverse strandRMDN3Diagram of PAK6: 11 exons on the forward strand of chromosome 15Exon 1: 40,239,063–40,239,802, 740 basesExon 2: 40,240,599–40,240,681, 83 basesExon 3: 40,253,178–40,253,289, 112 basesExon 4: 40,264,781–40,264,989, 209 basesExon 5: 40,265,842–40,266,495, 654 basesExon 6: 40,272,224–40,272,721, 498 basesExon 7: 40,272,866–40,272,999, 134 basesExon 8: 40,273,346–40,273,472, 127 basesExon 9: 40,273,551–40,273,676, 126 basesExon 10: 40,274,142–40,274,276, 135 basesExon 11: 40,275,927–40,277,487, 1,561 bases1246810115′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 4.4 kb of the gene's 38.4 kb; 2,046 of those bases code for the protein.

How a genome test reads PAK6

1

position in PAK6 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 38.4 kb of PAK6, introns included, not only the 4.4 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). PAK6 gene: p21 (RAC1) activated kinase 6. Retrieved 17 October 2026, from https://dantelabs.com/genes/pak6

Vancouver

Dante Labs. PAK6 gene: p21 (RAC1) activated kinase 6 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/pak6

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