Trait
Chronic oral thrush
Clinical name: Recurrent oral thrush
Chronic accumulation and overgrowth of the fungus Candida albicans on the mucous membranes of the mouth, generally manifested as associated with creamy white lesions on the tongue or inner cheeks, occasionally spreading to the gums, tonsils, palate or oropharynx.
Summary
- Also called
- Chronic oral candidiasis, Persistent oral thrush
Reference genomeGRCh38hg38
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Get my Genome Test37 genes linked to Chronic oral thrush
Changes in these genes cause rare conditions in which Chronic oral thrush is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| AIREautoimmune regulator | Always | In 1 condition |
| AP3B1adaptor related protein complex 3 subunit beta 1 | Always | In 1 condition |
| CD3GCD3 gamma subunit of T-cell receptor complex | Always | In 1 condition |
| CORO1Acoronin 1A | Always | In 1 condition |
| DCLRE1CDNA cross-link repair 1C | Always | In 2 conditions |
| IKBKBinhibitor of nuclear factor kappa B kinase subunit beta | Always | In 1 condition |
| IL2RAinterleukin 2 receptor subunit alpha | Always | In 1 condition |
| ITPR3inositol 1,4,5-trisphosphate receptor type 3 | Always | In 1 condition |
| LCKLCK proto-oncogene, Src family tyrosine kinase | Always | In 1 condition |
| MAN2B2mannosidase alpha class 2B member 2 | Always | In 1 condition |
| RAG1recombination activating 1 | Always | In 1 condition |
| RAG2recombination activating 2 | Always | In 1 condition |
| TRACT cell receptor alpha constant | Always | In 1 condition |
| TRAF3IP2TRAF3 interacting protein 2 | Always | In 1 condition |
| IL17RAinterleukin 17 receptor A | Very often (80–99%) | In 1 condition |
| CARD9caspase recruitment domain family member 9 | Often (30–79%) | In 1 condition |
| IL2RGinterleukin 2 receptor subunit gamma | Often (30–79%) | In 2 conditions |
| JAK3Janus kinase 3 | Often (30–79%) | In 1 condition |
| KNSTRNkinetochore localized astrin (SPAG5) binding protein | Often (30–79%) | In 1 condition |
| PIK3CDphosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta | Often (30–79%) | In 1 condition |
| RFX5regulatory factor X5 | Often (30–79%) | In 1 condition |
| RORCRAR related orphan receptor C | Often (30–79%) | In 1 condition |
| STAT3signal transducer and activator of transcription 3 | Often (30–79%) | In 1 condition |
| ZAP70zeta chain of T cell receptor associated protein kinase 70 | Often (30–79%) | In 1 condition |
| CD247CD247 molecule | Sometimes (5–29%) | In 1 condition |
| CD3DCD3 delta subunit of T-cell receptor complex | Sometimes (5–29%) | In 1 condition |
| CD3ECD3 epsilon subunit of T-cell receptor complex | Sometimes (5–29%) | In 1 condition |
| CD40LGCD40 ligand | Sometimes (5–29%) | In 1 condition |
| DOCK2dedicator of cytokinesis 2 | Sometimes (5–29%) | In 1 condition |
| FOXN1forkhead box N1 | Sometimes (5–29%) | In 1 condition |
| MVKmevalonate kinase | Sometimes (5–29%) | In 1 condition |
| NCF2neutrophil cytosolic factor 2 | Sometimes (5–29%) | In 1 condition |
| STAT1signal transducer and activator of transcription 1 | Sometimes (5–29%) | In 1 condition |
| TFRCtransferrin receptor | Sometimes (5–29%) | In 1 condition |
| TLR8toll like receptor 8 | Sometimes (5–29%) | In 1 condition |
| WDR1WD repeat domain 1 | Sometimes (5–29%) | In 1 condition |
| ZNF341zinc finger protein 341 | Sometimes (5–29%) | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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