Gene
GNAI3
G protein subunit alpha i3
- HGNC 4387↗(opens in a new tab)
- Ensembl gene ENSG00000065135↗(opens in a new tab)
- NCBI Gene 2773↗(opens in a new tab)
Summary
- Cytogenetic location
- 1p13.3
- Coordinates
- Chromosome 1: 109,548,615–109,600,195 (GRCh38)
- Exons
- 9 exons across 51.6 kb
- Protein
- 354 amino acids
- Also known as
- 87U6
- MANE Select transcript
- ENST00000369851.7NM_006496.4
- Locus type
- gene with protein product
- Very high
- Confident
- Low
- Very low
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
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No Genome Test report reads GNAI3 yet. The test sequences your whole genome, so your data includes it all the same.
How GNAI3 is laid out
- Coding sequence
- Untranslated region
- Intron
- Direction of transcription
- Known disease-causing sites
- Stretches short reads find hard
Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.
Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).
Nearby genes from Ensembl release 116, on GRCh38.
Exons make up 9 kb of the gene's 51.6 kb; 1,065 of those bases code for the protein.
How a genome test reads GNAI3
6
positions in GNAI3 where ClinVar classes a change as pathogenic or likely pathogenic
None of them falls in a region short reads find hard.
A whole genome covers all 51.6 kb of GNAI3, introns included, not only the 9 kb of exons.
Traits linked to GNAI3
The Human Phenotype Ontology lists these as features of the rare conditions GNAI3 can cause. Each trait's page lists the other genes linked to it.
Abnormality of head or neck
- Mandibular condyle hypoplasia
- Abnormality of the jaw joint
- Bad bite
- Bifid uvula
- Big calvaria
- Cleft palate
- Dental crowding
- Facial asymmetry
Show 14 more traits
- Full cheeks
- Little lower jaw
- Narrow mouth
- Pits around the ear
- Retraction of the tongue
- Skin tag in front of the ear
- Tongue muscle weakness
- Abnormally small tongue
- Hamartoma of tongue
- Mandibular condyle aplasia
- Absence of overlap of anterior upper and lower teeth
- Chewing difficulties
- Round face
- Skin tag behind the ear
External links
Gene records
Transcript
Protein
Where this comes from
- HGNC: the gene's symbol, name, other symbols and location.
- MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
- ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
- The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
Cite this page
Dante Labs. (n.d.). GNAI3 gene: G protein subunit alpha i3. Retrieved 16 October 2026, from https://dantelabs.com/genes/gnai3
Dante Labs. GNAI3 gene: G protein subunit alpha i3 [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/gnai3
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