Traits

Traits linked to DRG1

developmentally regulated GTP binding protein 1

The Human Phenotype Ontology links 25 traits to DRG1, by body system: features seen in people with one of the gene's rare conditions.

Abnormality of head or neck

Trait	How often it is seen
Abnormally small head	Always
Broad head shape	Always
Flattened bony protrusion above eyes	Always
Prominent forehead	Always
Short opening between the eyelids	Always
Wide nasal bridge	Always
Widely spaced teeth	Always
Drooping lower lip	Often (30–79%)
Short eyelashes	Often (30–79%)

Abnormality of the nervous system

Trait	How often it is seen
Neurodevelopmental delay	Always
Epilepsy	Sometimes (5–29%)
Myelomeningocele	Sometimes (5–29%)

Growth abnormality

Trait	How often it is seen
Faltering weight	Always
Prenatal growth deficiency	Always
Proportionate short stature	Always

Abnormality of the ear

Trait	How often it is seen
Low-set ears	Always
Ears rotated toward back of head	Often (30–79%)

Abnormality of the immune system

Trait	How often it is seen
Eczema	Always
Recurrent infections	Often (30–79%)

Abnormality of the musculoskeletal system

Trait	How often it is seen
Permanent flexion of the finger or toe	Always
Involuntary muscle stiffness, contraction, or spasm	Often (30–79%)

Abnormal cellular phenotype

Trait	How often it is seen
Increased antibody level in blood	Often (30–79%)

Abnormality of blood and blood-forming tissues

Trait	How often it is seen
Autoimmune hemolytic anemia	Often (30–79%)

Abnormality of limbs

Trait	How often it is seen
Club feet	Often (30–79%)

Abnormality of the integument

Trait	How often it is seen
Dry skin	Often (30–79%)

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Where this comes from

The Human Phenotype Ontology, release 2026-09-01: the traits linked to DRG1 and how often each is seen. Find out more at hpo.jax.org.

One test. A lifetime of answers.

From $449Free shipping · Results in 6–8 weeks

Get my Genome Test