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Gene

CACNB4

calcium voltage-gated channel auxiliary subunit beta 4

Summary

Cytogenetic location
2q23.3
Coordinates
Chromosome 2: 151,832,771–152,099,044 (GRCh38)
Exons
14 exons across 266.3 kb
Protein
520 amino acids
Also known as
EJM4
MANE Select transcript
ENST00000539935.7NM_000726.5
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads CACNB4 yet. The test sequences your whole genome, so your data includes it all the same.

How CACNB4 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 2, with a bracket where CACNB4 sits. CACNB4 and 6 genes near it on chromosome 2, from 151,465,908 to 152,465,907.Chromosome 22q23.3p25.3p25.2p25.1p24.3p24.2p24.1p23.3p23.2p23.1p22.3p22.2p22.1p21p16.3p16.2p16.1p15p14p13.3p13.2p13.1p12p11.2p11.1q11.1q11.2q12.1q12.2q12.3q13q14.1q14.2q14.3q21.1q21.2q21.3q22.1q22.2q22.3q23.1q23.2q23.3q24.1q24.2q24.3q31.1q31.2q31.3q32.1q32.2q32.3q33.1q33.2q33.3q34q35q36.1q36.2q36.3q37.1q37.2q37.3151.6 Mb151.8 Mb152 Mb152.2 Mb152.4 MbRIF1: 151,409,883–151,508,013, forward strandRIF1NEB: 151,485,336–151,734,515, reverse strandNEBARL5A: 151,766,233–151,828,531, reverse strandARL5A: 151,802,651–151,973,949, reverse strandCACNB4: 151,832,771–152,099,044, reverse strandCACNB4STAM2: 152,116,801–152,175,781, reverse strandSTAM2FMNL2: 152,335,113–152,649,831, forward strandFMNL2Diagram of CACNB4: 14 exons on the reverse strand of chromosome 2Exon 3: 1 known disease-causing siteExon 14: 151,832,771–151,839,379, 6,609 basesExon 13: 151,841,903–151,842,088, 186 basesExon 12: 151,853,448–151,853,543, 96 basesExon 11: 151,855,224–151,855,375, 152 basesExon 10: 151,860,711–151,860,820, 110 basesExon 9: 151,869,177–151,869,235, 59 basesExon 8: 151,870,531–151,870,611, 81 basesExon 7: 151,870,842–151,870,861, 20 basesExon 6: 151,872,417–151,872,493, 77 basesExon 5: 151,876,426–151,876,556, 131 basesExon 4: 151,880,800–151,880,922, 123 basesExon 3: 151,883,251–151,883,370, 120 basesExon 2: 152,098,330–152,098,413, 84 basesExon 1: 152,098,949–152,099,044, 96 bases1410515′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 7.9 kb of the gene's 266.3 kb; 1,563 of those bases code for the protein.

How a genome test reads CACNB4

1

position in CACNB4 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 266.3 kb of CACNB4, introns included, not only the 7.9 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). CACNB4 gene: calcium voltage-gated channel auxiliary subunit beta 4. Retrieved 16 October 2026, from https://dantelabs.com/genes/cacnb4

Vancouver

Dante Labs. CACNB4 gene: calcium voltage-gated channel auxiliary subunit beta 4 [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/cacnb4

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