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Gene

ARIH1

ariadne RBR E3 ubiquitin protein ligase 1

Summary

Cytogenetic location
15q24.1
Coordinates
Chromosome 15: 72,474,330–72,602,987 (GRCh38)
Exons
14 exons across 128.7 kb
Protein
557 amino acids
Also known as
HARI, HHARI, UBCH7BP, ARI
MANE Select transcript
ENST00000379887.9NM_005744.5
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated report relevant to this gene

  • Aortic Aneurysm

    • An aneurysm formed in the wall of the proximal portion of the descending aorta proceeding from the arch of the aorta.

      • 1 GenCC submitter rates it definitive or strong
      What knowing changes

      Beta-blockers, angiotensin II receptor antagonists, prophylactic aortic root replacement, activity restriction

How ARIH1 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 15, with a bracket where ARIH1 sits. ARIH1 and 14 genes near it on chromosome 15, from 72,038,659 to 73,038,658.Chromosome 1515q24.1p13p12p11.2p11.1q11.1q11.2q12q13.1q13.2q13.3q14q15.1q15.2q15.3q21.1q21.2q21.3q22.1q22.2q22.31q22.32q22.33q23q24.1q24.2q24.3q25.1q25.2q25.3q26.1q26.2q26.372.2 Mb72.4 Mb72.6 Mb72.8 Mb73 MbMYO9A: 71,822,291–72,118,577, reverse strandMYO9ASENP8: 72,114,258–72,143,692, forward strandSENP8GRAMD2A: 72,159,806–72,197,830, reverse strandGRAMD2APKM: 72,199,024–72,231,819, reverse strandPKMPARP6: 72,241,176–72,272,999, reverse strandPARP6: 72,266,746–72,319,946, reverse strand: 72,284,727–72,375,981, reverse strandCELF6: 72,284,727–72,320,622, reverse strandCELF6HEXA: 72,340,919–72,376,420, reverse strandHEXATMEM202: 72,398,302–72,408,367, forward strandTMEM202ARIH1: 72,474,330–72,602,987, forward strandARIH1GOLGA6B: 72,654,697–72,669,599, forward strandGOLGA6BHIGD2B: 72,675,791–72,686,621, reverse strandHIGD2BBBS4: 72,686,181–72,742,006, forward strandBBS4ADPGK: 72,735,951–72,785,846, reverse strandADPGKDiagram of ARIH1: 14 exons on the forward strand of chromosome 15Exon 1: 72,474,330–72,475,014, 685 basesExon 2: 72,518,067–72,518,134, 68 basesExon 3: 72,544,820–72,544,964, 145 basesExon 4: 72,555,271–72,555,363, 93 basesExon 5: 72,555,852–72,555,907, 56 basesExon 6: 72,561,483–72,561,549, 67 basesExon 7: 72,563,394–72,563,500, 107 basesExon 8: 72,566,563–72,566,605, 43 basesExon 9: 72,567,106–72,567,177, 72 basesExon 10: 72,570,177–72,570,307, 131 basesExon 11: 72,572,108–72,572,165, 58 basesExon 12: 72,580,731–72,580,991, 261 basesExon 13: 72,582,075–72,582,187, 113 basesExon 14: 72,583,208–72,602,987, 19,780 bases124681012145′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 21.7 kb of the gene's 128.7 kb; 1,674 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • GenCC and ClinGen, released 2026-10-16: which conditions the gene is linked to, and how strongly.
  • The ACMG secondary findings list, SF v3.2.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). ARIH1 gene: ariadne RBR E3 ubiquitin protein ligase 1. Retrieved 17 October 2026, from https://dantelabs.com/genes/arih1

Vancouver

Dante Labs. ARIH1 gene: ariadne RBR E3 ubiquitin protein ligase 1 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/arih1

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