Trait
Skin erosion
A discontinuity of the skin exhibiting incomplete loss of the epidermis, a lesion that is moist, circumscribed, and usually depressed.
Summary
- Body system
- Abnormality of the integument
Reference genomeGRCh38hg38
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Get my Genome Test29 genes linked to Skin erosion
Changes in these genes cause rare conditions in which Skin erosion is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| DSPdesmoplakin | Always | In 1 condition |
| KRT1keratin 1 | Always | In 1 condition |
| KRT10keratin 10 | Always | In 1 condition |
| PPOXprotoporphyrinogen oxidase | Always | In 2 conditions |
| ZMPSTE24zinc metallopeptidase STE24 | Always | In 2 conditions |
| ARL6IP6ARF like GTPase 6 interacting protein 6 | Very often (80–99%) | In 1 condition |
| ATP2C1ATPase secretory pathway Ca2+ transporting 1 | Very often (80–99%) | In 1 condition |
| COL2A1collagen type II alpha 1 chain | Very often (80–99%) | In 1 condition |
| GNA11G protein subunit alpha 11 | Very often (80–99%) | In 1 condition |
| LAMA3laminin subunit alpha 3 | Very often (80–99%) | In 2 conditions |
| LAMB3laminin subunit beta 3 | Very often (80–99%) | In 1 condition |
| LAMC2laminin subunit gamma 2 | Very often (80–99%) | In 1 condition |
| LMNAlamin A/C | Very often (80–99%) | In 1 condition |
| COL7A1collagen type VII alpha 1 chain | Often (30–79%) | In 4 conditions |
| EPHB4EPH receptor B4 | Often (30–79%) | In 1 condition |
| GATA1GATA binding protein 1 | Often (30–79%) | In 1 condition |
| ITGB4integrin subunit beta 4 | Often (30–79%) | In 1 condition |
| KRT14keratin 14 | Often (30–79%) | In 2 conditions |
| KRT5keratin 5 | Often (30–79%) | In 2 conditions |
| PLECplectin | Often (30–79%) | In 2 conditions |
| PORCNporcupine O-acyltransferase | Often (30–79%) | In 1 condition |
| URODuroporphyrinogen decarboxylase | Often (30–79%) | In 1 condition |
| UROSuroporphyrinogen III synthase | Often (30–79%) | In 1 condition |
| CSTAcystatin A | Sometimes (5–29%) | In 1 condition |
| ECM1extracellular matrix protein 1 | Sometimes (5–29%) | In 1 condition |
| KITKIT proto-oncogene, receptor tyrosine kinase | Sometimes (5–29%) | In 1 condition |
| TGM5transglutaminase 5 | Sometimes (5–29%) | In 1 condition |
| NAXENAD(P)HX epimerase | Not recorded | In 1 condition |
| RIPK4receptor interacting serine/threonine kinase 4 | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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