Trait
Primitive reflex
The primitive reflexes are a group of behavioral motor responses which are found in normal early development, are subsequently inhibited, but may be released from inhibition by cerebral, usually frontal, damage. They are thus part of a broader group of reflexes which reflect release phenomena, such as exaggerated stretch reflexes and extensor plantars. They do however involve more complex motor responses than such simple stretch reflexes, and are often a normal feature in the neonate or infant.
Summary
- Also called
- Archaic reflex, Primitive reflexes
- Body system
- Abnormality of the nervous system
Reference genomeGRCh38hg38
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Get my Genome Test19 genes linked to Primitive reflex
Changes in these genes cause rare conditions in which Primitive reflex is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| DCTN1dynactin subunit 1 | Always | In 1 condition |
| GTPBP2GTP binding protein 2 | Always | In 1 condition |
| NDUFS8NADH:ubiquinone oxidoreductase core subunit S8 | Always | In 1 condition |
| ST3GAL3ST3 beta-galactoside alpha-2,3-sialyltransferase 3 | Always | In 1 condition |
| GM2Aganglioside GM2 activator | Often (30–79%) | In 2 conditions |
| SPG21SPG21 abhydrolase domain containing, maspardin | Often (30–79%) | In 2 conditions |
| ALDH18A1aldehyde dehydrogenase 18 family member A1 | Sometimes (5–29%) | In 1 condition |
| DNMT1DNA methyltransferase 1 | Sometimes (5–29%) | In 2 conditions |
| JPH3junctophilin 3 | Sometimes (5–29%) | In 1 condition |
| RAB18RAB18, member RAS oncogene family | Sometimes (5–29%) | In 1 condition |
| HADHAhydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha | Rarely (1–4%) | In 1 condition |
| HADHBhydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta | Rarely (1–4%) | In 1 condition |
| CTSFcathepsin F | Not recorded | In 1 condition |
| DPM2dolichyl-phosphate mannosyltransferase subunit 2, regulatory | Not recorded | In 1 condition |
| MAPTmicrotubule associated protein tau | Not recorded | In 2 conditions |
| PIEZO2piezo type mechanosensitive ion channel component 2 | Not recorded | In 1 condition |
| PSEN1presenilin 1 | Not recorded | In 2 conditions |
| TREM2triggering receptor expressed on myeloid cells 2 | Not recorded | In 2 conditions |
| TYROBPtransmembrane immune signaling adaptor TYROBP | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
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Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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