Trait
Paranoia
The feeling and belief that one is being targeted or is a focus of negative or untoward actions, overt or covert, from others. The affected individual expresses a concern that people are in general against the individual and are engaging in subtle behaviors to make things difficult for them. The origins of such thinking may arise from real events and become amplified over time. Paranoia may also arise in the absence of any action or interaction between the person and their environment.
Summary
- Body system
- Abnormality of the nervous system
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
Read the genes linked to Paranoia, and the rest of your genome, with one test.
From $449Free shipping · Results in 6–8 weeks
Get my Genome Test24 genes linked to Paranoia
Changes in these genes cause rare conditions in which Paranoia is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| IMPA1inositol monophosphatase 1 | Often (30–79%) | In 1 condition |
| FMO3flavin containing dimethylaniline monoxygenase 3 | Sometimes (5–29%) | In 1 condition |
| HMBShydroxymethylbilane synthase | Sometimes (5–29%) | In 1 condition |
| PLA2G6phospholipase A2 group VI | Sometimes (5–29%) | In 1 condition |
| TIMM8Atranslocase of inner mitochondrial membrane 8A | Sometimes (5–29%) | In 1 condition |
| VPS13Avacuolar protein sorting 13 homolog A | Sometimes (5–29%) | In 1 condition |
| ATRXATRX chromatin remodeler | Rarely (1–4%) | In 1 condition |
| BRAFB-Raf proto-oncogene, serine/threonine kinase | Rarely (1–4%) | In 1 condition |
| CDH23cadherin related 23 | Rarely (1–4%) | In 1 condition |
| NR3C1nuclear receptor subfamily 3 group C member 1 | Rarely (1–4%) | In 1 condition |
| PPOXprotoporphyrinogen oxidase | Rarely (1–4%) | In 1 condition |
| PRDM8PR/SET domain 8 | Rarely (1–4%) | In 2 conditions |
| TP53tumor protein p53 | Rarely (1–4%) | In 1 condition |
| USP48ubiquitin specific peptidase 48 | Rarely (1–4%) | In 1 condition |
| USP8ubiquitin specific peptidase 8 | Rarely (1–4%) | In 1 condition |
| CPOXcoproporphyrinogen oxidase | Not recorded | In 1 condition |
| DGCR2DiGeorge syndrome critical region gene 2 | Not recorded | In 1 condition |
| DGCR6DiGeorge syndrome critical region gene 6 | Not recorded | In 1 condition |
| DGCR8DGCR8 microprocessor complex subunit | Not recorded | In 1 condition |
| ECM1extracellular matrix protein 1 | Not recorded | In 1 condition |
| ESS2ess-2 spliceosome associated protein | Not recorded | In 1 condition |
| SNCAsynuclein alpha | Not recorded | In 1 condition |
| TBPTATA-box binding protein | Not recorded | In 1 condition |
| TBX1T-box transcription factor 1 | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
One test. A lifetime of answers.
From $449Free shipping · Results in 6–8 weeks