Trait
Microlissencephaly
Severe microcephaly and lissencephaly with granular surfaces with immature cortical plate, reduced in thickness, with focal polymicrogyria and immature small neurons with rare processes, intermingled with a considerable number of glial elements.
Summary
- Also called
- Lissencephaly type III, Type 3 lissencephaly, Type III lissencephaly
- Body system
- Abnormality of the nervous system
Reference genomeGRCh38hg38
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Get my Genome Test6 genes linked to Microlissencephaly
Changes in these genes cause rare conditions in which Microlissencephaly is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| KATNB1katanin regulatory subunit B1 | Very often (80–99%) | In 2 conditions |
| NDE1nudE neurodevelopment protein 1 | Very often (80–99%) | In 1 condition |
| RELNreelin | Very often (80–99%) | In 1 condition |
| KIF14kinesin family member 14 | Sometimes (5–29%) | In 1 condition |
| RNU4ATACRNA, U4atac small nuclear | Sometimes (5–29%) | In 1 condition |
| CITcitron rho-interacting serine/threonine kinase | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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