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Gene

NDE1

nudE neurodevelopment protein 1

Summary

Cytogenetic location
16p13.11
Coordinates
Chromosome 16: 15,650,245–15,726,353 (GRCh38)
Exons
9 exons across 76.1 kb
Protein
335 amino acids
Also known as
nudE, FLJ20101, NDE
MANE Select transcript
ENST00000396354.6NM_017668.3
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads NDE1 yet. The test sequences your whole genome, so your data includes it all the same.

How NDE1 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 16, with a bracket where NDE1 sits. NDE1 and 9 genes near it on chromosome 16, from 15,188,299 to 16,188,298.Chromosome 1616p13.11p13.3p13.2p13.13p13.12p13.11p12.3p12.2p12.1p11.2p11.1q11.1q11.2q12.1q12.2q13q21q22.1q22.2q22.3q23.1q23.2q23.3q24.1q24.2q24.315.2 Mb15.4 Mb15.6 Mb15.8 Mb16 MbNPIPA5: 15,363,628–15,381,047, reverse strandNPIPA5MPV17L: 15,395,747–15,413,271, forward strandMPV17L: 15,395,754–15,515,348, forward strandBMERB1: 15,434,475–15,625,028, forward strandBMERB1MARF1: 15,594,302–15,643,209, reverse strandMARF1NDE1: 15,650,245–15,726,353, forward strandNDE1MYH11: 15,703,135–15,858,438, reverse strandMYH11CEP20: 15,865,719–15,888,644, reverse strandCEP20ABCC1: 15,949,138–16,143,257, forward strandABCC1ABCC6: 16,149,565–16,223,637, reverse strandABCC6Diagram of NDE1: 9 exons on the forward strand of chromosome 16Exon 3: 2 known disease-causing sitesExon 6: 2 known disease-causing sitesExon 7: 1 known disease-causing siteExon 1: 15,650,245–15,650,294, 50 basesExon 2: 15,664,736–15,664,861, 126 basesExon 3: 15,667,286–15,667,439, 154 basesExon 4: 15,677,801–15,677,949, 149 basesExon 5: 15,687,375–15,687,511, 137 basesExon 6: 15,691,144–15,691,323, 180 basesExon 7: 15,694,165–15,694,256, 92 basesExon 8: 15,696,709–15,696,860, 152 basesExon 9: 15,724,191–15,726,353, 2,163 bases1234567895′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 3.2 kb of the gene's 76.1 kb; 1,008 of those bases code for the protein.

How a genome test reads NDE1

7

positions in NDE1 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 76.1 kb of NDE1, introns included, not only the 3.2 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). NDE1 gene: nudE neurodevelopment protein 1. Retrieved 16 October 2026, from https://dantelabs.com/genes/nde1

Vancouver

Dante Labs. NDE1 gene: nudE neurodevelopment protein 1 [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/nde1

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