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Gene

VIM

vimentin

Summary

Cytogenetic location
10p13
Coordinates
Chromosome 10: 17,228,241–17,237,593 (GRCh38)
Exons
10 exons across 9.4 kb
Protein
466 amino acids
MANE Select transcript
ENST00000544301.7NM_003380.5
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated report relevant to this gene

  • Hereditary Congenital & Juvenile Cataract

    • Early-Onset Non-Syndromic Cataract

      Cataract that appears at birth or early in life without other features, caused by changes in lens genes such as the crystallins (CRYAA, CRYBB2, CRYGD and others), GJA3, GJA8 and MIP.

      • 2 GenCC submitters rate it definitive or strong
      What knowing changes

      Early detection and surgery in children help prevent permanent vision loss from amblyopia, and family members can be offered eye checks.

How VIM is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
Chromosome 10, with a bracket where VIM sits. VIM and 6 genes near it on chromosome 10, from 16,732,917 to 17,732,916.Chromosome 1010p13p15.3p15.2p15.1p14p13p12.33p12.32p12.31p12.2p12.1p11.23p11.22p11.21p11.1q11.1q11.21q11.22q11.23q21.1q21.2q21.3q22.1q22.2q22.3q23.1q23.2q23.31q23.32q23.33q24.1q24.2q24.31q24.32q24.33q25.1q25.2q25.3q26.11q26.12q26.13q26.2q26.316.8 Mb17 Mb17.2 Mb17.4 Mb17.6 MbRSU1: 16,567,276–16,817,603, reverse strandRSU1CUBN: 16,823,966–17,129,970, reverse strandCUBNTRDMT1: 17,137,336–17,202,054, reverse strandTRDMT1VIM: 17,228,241–17,237,593, forward strandVIMST8SIA6: 17,315,416–17,454,681, reverse strandST8SIA6HACD1: 17,588,301–17,617,566, reverse strandHACD1STAM: 17,644,124–17,735,901, forward strandSTAMDiagram of VIM: 10 exons on the forward strand of chromosome 10Exon 1: 17,228,241–17,228,524, 284 basesExon 2: 17,229,276–17,229,985, 710 basesExon 3: 17,230,650–17,230,710, 61 basesExon 4: 17,233,587–17,233,682, 96 basesExon 5: 17,233,770–17,233,931, 162 basesExon 6: 17,234,693–17,234,818, 126 basesExon 7: 17,235,169–17,235,389, 221 basesExon 8: 17,235,846–17,235,889, 44 basesExon 9: 17,236,294–17,236,379, 86 basesExon 10: 17,237,230–17,237,593, 364 bases123456789105′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 2.2 kb of the gene's 9.4 kb; 1,401 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • GenCC and ClinGen, released 2026-10-16: which conditions the gene is linked to, and how strongly.
  • The ACMG secondary findings list, SF v3.2.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). VIM gene: vimentin. Retrieved 17 October 2026, from https://dantelabs.com/genes/vim

Vancouver

Dante Labs. VIM gene: vimentin [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/vim

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