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Gene

SMOC1

SPARC related modular calcium binding 1

Summary

Cytogenetic location
14q24.1
Coordinates
Chromosome 14: 69,879,416–70,032,366 (GRCh38)
Exons
12 exons across 153 kb
Protein
435 amino acids
MANE Select transcript
ENST00000361956.8NM_001034852.3
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads SMOC1 yet. The test sequences your whole genome, so your data includes it all the same.

How SMOC1 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 14, with a bracket where SMOC1 sits. SMOC1 and 11 genes near it on chromosome 14, from 69,455,891 to 70,455,890.Chromosome 1414q24.1p13p12p11.2p11.1q11.1q11.2q12q13.1q13.2q13.3q21.1q21.2q21.3q22.1q22.2q22.3q23.1q23.2q23.3q24.1q24.2q24.3q31.1q31.2q31.3q32.11q32.12q32.13q32.2q32.31q32.32q32.3369.6 Mb69.8 Mb70 Mb70.2 Mb70.4 MbSLC39A9: 69,398,015–69,463,644, forward strandSLC39A9PLEKHD1: 69,484,692–69,531,551, forward strandPLEKHD1CCDC177: 69,569,498–69,574,890, reverse strandCCDC177SUSD6: 69,611,567–69,715,144, forward strandSUSD6SRSF5: 69,726,822–69,773,904, forward strandSRSF5SLC10A1: 69,768,055–69,797,665, reverse strandSLC10A1SMOC1: 69,879,416–70,032,366, forward strandSMOC1SLC8A3: 70,044,215–70,189,480, reverse strandSLC8A3COX16: 70,325,081–70,416,984, reverse strandCOX16SYNJ2BP-COX16: 70,326,064–70,417,074, reverse strandSYNJ2BP-COX16SYNJ2BP: 70,366,499–70,417,102, reverse strandSYNJ2BPADAM21: 70,417,107–70,460,453, forward strandADAM21Diagram of SMOC1: 12 exons on the forward strand of chromosome 14Exon 2: 1 known disease-causing siteExon 4: 1 known disease-causing siteExon 5: 1 known disease-causing siteExon 1: 69,879,416–69,879,777, 362 basesExon 2: 69,952,138–69,952,303, 166 basesExon 3: 69,953,420–69,953,532, 113 basesExon 4: 69,975,715–69,975,814, 100 basesExon 5: 69,977,918–69,977,965, 48 basesExon 6: 69,992,417–69,992,473, 57 basesExon 7: 69,994,400–69,994,480, 81 basesExon 8: 70,010,754–70,010,946, 193 basesExon 9: 70,011,485–70,011,567, 83 basesExon 10: 70,013,386–70,013,491, 106 basesExon 11: 70,023,203–70,023,447, 245 basesExon 12: 70,030,242–70,032,366, 2,125 bases1510125′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 3.7 kb of the gene's 153 kb; 1,308 of those bases code for the protein.

How a genome test reads SMOC1

4

positions in SMOC1 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 153 kb of SMOC1, introns included, not only the 3.7 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). SMOC1 gene: SPARC related modular calcium binding 1. Retrieved 17 October 2026, from https://dantelabs.com/genes/smoc1

Vancouver

Dante Labs. SMOC1 gene: SPARC related modular calcium binding 1 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/smoc1

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