Traits

Traits linked to PALLD

palladin, cytoskeletal associated protein

The Human Phenotype Ontology links 24 traits to PALLD, by body system: features seen in people with one of the gene's rare conditions.

Abnormality of the digestive system

Trait	How often it is seen
Pancreatic adenocarcinoma	Always
Abdominal pain	Very often (80–99%)
Anorexia	Very often (80–99%)
Inability to properly digest food due to lack of pancreatic digestive enzymes	Very often (80–99%)
Poor appetite	Very often (80–99%)
Extrahepatic cholestasis	Often (30–79%)
Functional intestinal obstruction	Often (30–79%)
Intestinal pseudo-obstruction	Often (30–79%)
Jaundice	Often (30–79%)
Colon cancer	Sometimes (5–29%)
Intermittent diarrhea	Sometimes (5–29%)
Liver cancer	Sometimes (5–29%)
Nausea and vomiting	Sometimes (5–29%)
Peritoneal abscess	Sometimes (5–29%)

Abnormality of the cardiovascular system

Trait	How often it is seen
Swollen lymph nodes	Often (30–79%)
Enlarged liver and spleen	Sometimes (5–29%)

Laboratory abnormality

Trait	How often it is seen
Diabetes mellitus	Sometimes (5–29%)
High liver enzymes	Sometimes (5–29%)

Abnormal tissue mass

Trait	How often it is seen
Cancer of skin pigment cells	Sometimes (5–29%)

Abnormality of the breast

Trait	How often it is seen
Breast cancer	Sometimes (5–29%)

Abnormality of the genitourinary system

Trait	How often it is seen
Ovarian carcinoma	Sometimes (5–29%)

Abnormality of the musculoskeletal system

Trait	How often it is seen
Back pain	Very often (80–99%)

Constitutional symptom

Trait	How often it is seen
Chronic fatigue	Very often (80–99%)

Growth abnormality

Trait	How often it is seen
Weight loss	Very often (80–99%)

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Where this comes from

The Human Phenotype Ontology, release 2026-09-01: the traits linked to PALLD and how often each is seen. Find out more at hpo.jax.org.

One test. A lifetime of answers.

From $449Free shipping · Results in 6–8 weeks

Get my Genome Test