Trait

Chronic liver failure

Clinical name: Chronic hepatic failure

Body system: Abnormality of the digestive system

This page as data

Add .json to the page's address, or ask for application/json, to read it as JSON.

library(jsonlite)

url <- "https://dantelabs.com/traits/chronic-hepatic-failure.json"
page <- fromJSON(url)
page$trait$name

Open the JSON

Read the genes linked to Chronic liver failure, and the rest of your genome, with one test.

From $449Free shipping · Results in 6–8 weeks

Get my Genome Test

14 genes linked to Chronic liver failure

Changes in these genes cause rare conditions in which Chronic liver failure is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.

Gene	How often it is seen	Conditions
HADHAhydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha	Often (30–79%)	In 1 condition
HADHBhydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta	Often (30–79%)	In 1 condition
ALDOBaldolase, fructose-bisphosphate B	Sometimes (5–29%)	In 1 condition
BMP6bone morphogenetic protein 6	Sometimes (5–29%)	In 1 condition
CC2D2Acoiled-coil and C2 domain containing 2A	Sometimes (5–29%)	In 1 condition
GPR35G protein-coupled receptor 35	Sometimes (5–29%)	In 1 condition
HFEhomeostatic iron regulator	Sometimes (5–29%)	In 1 condition
INPP5Einositol polyphosphate-5-phosphatase E	Sometimes (5–29%)	In 1 condition
MST1macrophage stimulating 1	Sometimes (5–29%)	In 1 condition
RPGRIP1LRPGRIP1 like	Sometimes (5–29%)	In 1 condition
SEMA4Dsemaphorin 4D	Sometimes (5–29%)	In 1 condition
SP110SP110 nuclear body protein	Sometimes (5–29%)	In 1 condition
TCF4transcription factor 4	Sometimes (5–29%)	In 1 condition
TMEM67transmembrane protein 67	Sometimes (5–29%)	In 1 condition

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Broader traits

Liver failure

Where this comes from

The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
Data release 2026.10.16-c6eea6bf.

One test. A lifetime of answers.