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Gene

APEH

acylaminoacyl-peptide hydrolase

Summary

Cytogenetic location
3p21.31
Coordinates
Chromosome 3: 49,674,351–49,683,971 (GRCh38)
Exons
22 exons across 9.6 kb
Protein
732 amino acids
Previous symbols
D3F15S2, DNF15S2, D3S48E
MANE Select transcript
ENST00000296456.10NM_001640.4
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads APEH yet. The test sequences your whole genome, so your data includes it all the same.

How APEH is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
Chromosome 3, with a bracket where APEH sits. APEH and 28 genes near it on chromosome 3, from 49,179,161 to 50,179,160.Chromosome 33p21.31p26.3p26.2p26.1p25.3p25.2p25.1p24.3p24.2p24.1p23p22.3p22.2p22.1p21.33p21.32p21.31p21.2p21.1p14.3p14.2p14.1p13p12.3p12.2p12.1p11.2p11.1q11.1q11.2q12.1q12.2q12.3q13.11q13.12q13.13q13.2q13.31q13.32q13.33q21.1q21.2q21.3q22.1q22.2q22.3q23q24q25.1q25.2q25.31q25.32q25.33q26.1q26.2q26.31q26.32q26.33q27.1q27.2q27.3q28q2949.2 Mb49.4 Mb49.6 Mb49.8 Mb50 MbCIMIP7: 49,177,634–49,191,858, reverse strandCIMIP7IHO1: 49,198,428–49,277,629, forward strandIHO1C3orf62: 49,268,596–49,277,236, reverse strandC3orf62USP4: 49,277,144–49,340,712, reverse strandUSP4GPX1: 49,357,174–49,358,605, reverse strandGPX1: 49,357,176–49,412,051, reverse strandRHOA: 49,359,136–49,412,998, reverse strandTCTA: 49,412,212–49,455,826, forward strandTCTAAMT: 49,416,771–49,422,685, reverse strandAMT: 49,416,777–49,429,314, reverse strandNICN1: 49,422,333–49,429,331, reverse strandNICN1DAG1: 49,468,649–49,535,624, forward strandDAG1BSN: 49,554,477–49,671,549, forward strandBSNAPEH: 49,674,351–49,683,971, forward strandAPEHMST1: 49,683,922–49,689,501, reverse strandMST1RNF123: 49,688,740–49,723,389, forward strandRNF123AMIGO3: 49,716,829–49,719,684, reverse strandAMIGO3GMPPB: 49,716,844–49,723,988, reverse strandIP6K1: 49,724,294–49,786,557, reverse strandIP6K1CDHR4: 49,790,732–49,799,879, reverse strandCDHR4INKA1: 49,803,228–49,805,237, forward strandINKA1UBA7: 49,805,205–49,814,151, reverse strandUBA7TRAIP: 49,828,595–49,856,597, reverse strandTRAIPCAMKV: 49,857,214–49,870,064, reverse strandCAMKVMST1R: 49,886,902–49,906,130, reverse strandMST1RMON1A: 49,907,160–49,930,173, reverse strandMON1ARBM6: 49,940,007–50,100,045, forward strandRBM6RBM5: 50,088,898–50,119,021, forward strandRBM5SEMA3F: 50,155,012–50,189,075, forward strandSEMA3FDiagram of APEH: 22 exons on the forward strand of chromosome 3Exon 1: 49,674,351–49,674,413, 63 basesExon 2: 49,674,489–49,674,621, 133 basesExon 3: 49,675,183–49,675,309, 127 basesExon 4: 49,675,694–49,675,787, 94 basesExon 5: 49,675,891–49,675,966, 76 basesExon 6: 49,676,056–49,676,219, 164 basesExon 7: 49,676,378–49,676,515, 138 basesExon 8: 49,676,609–49,676,700, 92 basesExon 9: 49,676,777–49,676,817, 41 basesExon 10: 49,676,903–49,677,024, 122 basesExon 11: 49,677,573–49,677,633, 61 basesExon 12: 49,678,852–49,678,949, 98 basesExon 13: 49,679,593–49,679,644, 52 basesExon 14: 49,680,541–49,680,629, 89 basesExon 15: 49,681,101–49,681,239, 139 basesExon 16: 49,681,722–49,681,805, 84 basesExon 17: 49,681,887–49,681,967, 81 basesExon 18: 49,682,348–49,682,436, 89 basesExon 19: 49,682,546–49,682,736, 191 basesExon 20: 49,682,843–49,682,945, 103 basesExon 21: 49,683,040–49,683,146, 107 basesExon 22: 49,683,237–49,683,971, 735 bases12468101214161820225′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 2.9 kb of the gene's 9.6 kb; 2,199 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.

Cite this page

APA

Dante Labs. (n.d.). APEH gene: acylaminoacyl-peptide hydrolase. Retrieved 16 October 2026, from https://dantelabs.com/genes/apeh

Vancouver

Dante Labs. APEH gene: acylaminoacyl-peptide hydrolase [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/apeh

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