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Gene

COL27A1

collagen type XXVII alpha 1 chain

Summary

Cytogenetic location
9q32
Coordinates
Chromosome 9: 114,155,537–114,312,511 (GRCh38)
Exons
61 exons across 157 kb
Protein
1,860 amino acids
Also known as
KIAA1870, MGC11337, FLJ11895
MANE Select transcript
ENST00000356083.8NM_032888.4
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads COL27A1 yet. The test sequences your whole genome, so your data includes it all the same.

How COL27A1 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 9, with a bracket where COL27A1 sits. COL27A1 and 11 genes near it on chromosome 9, from 113,734,024 to 114,734,023.Chromosome 99q32p24.3p24.2p24.1p23p22.3p22.2p22.1p21.3p21.2p21.1p13.3p13.2p13.1p12p11.2p11.1q11q12q13q21.11q21.12q21.13q21.2q21.31q21.32q21.33q22.1q22.2q22.31q22.32q22.33q31.1q31.2q31.3q32q33.1q33.2q33.3q34.11q34.12q34.13q34.2q34.3113.8 Mb114 Mb114.2 Mb114.4 Mb114.6 MbZNF618: 113,876,052–114,056,593, forward strandZNF618AMBP: 114,060,127–114,080,970, reverse strandAMBPKIF12: 114,086,126–114,099,370, reverse strandKIF12COL27A1: 114,155,537–114,312,511, forward strandCOL27A1ORM1: 114,322,951–114,326,970, forward strandORM1ORM2: 114,329,777–114,333,741, forward strandORM2AKNA: 114,334,156–114,394,405, reverse strandAKNAWHRN: 114,402,078–114,505,530, reverse strandWHRNATP6V1G1: 114,587,572–114,598,915, forward strandATP6V1G1TMEM268: 114,611,206–114,646,422, forward strandTMEM268TEX53: 114,656,302–114,662,374, reverse strandTEX53TEX48: 114,666,434–114,682,192, reverse strandTEX48Diagram of COL27A1: 61 exons on the forward strand of chromosome 9Exon 1: 1 known disease-causing siteExon 2: 1 known disease-causing siteExon 3: 6 known disease-causing sitesExon 7: 2 known disease-causing sitesExon 11: 1 known disease-causing siteExon 12: 1 known disease-causing siteExon 13: 1 known disease-causing siteExon 25: 1 known disease-causing siteExon 26: 2 known disease-causing sitesExon 33: 1 known disease-causing siteExon 37: 1 known disease-causing siteExon 42: 2 known disease-causing sitesExon 43: 1 known disease-causing siteExon 47: 2 known disease-causing sitesExon 49: 1 known disease-causing siteExon 52: 1 known disease-causing siteExon 56: 1 known disease-causing siteExon 59: 1 known disease-causing siteExon 1: 114,155,537–114,156,012, 476 basesExon 2: 114,162,715–114,162,785, 71 basesExon 3: 114,167,689–114,169,463, 1,775 basesExon 4: 114,178,291–114,178,344, 54 basesExon 5: 114,183,022–114,183,075, 54 basesExon 6: 114,194,404–114,194,457, 54 basesExon 7: 114,195,959–114,196,012, 54 basesExon 8: 114,205,102–114,205,146, 45 basesExon 9: 114,205,759–114,205,812, 54 basesExon 10: 114,206,252–114,206,296, 45 basesExon 11: 114,209,675–114,209,728, 54 basesExon 12: 114,210,982–114,211,026, 45 basesExon 13: 114,219,791–114,219,844, 54 basesExon 14: 114,222,223–114,222,267, 45 basesExon 15: 114,231,079–114,231,132, 54 basesExon 16: 114,231,822–114,231,866, 45 basesExon 17: 114,235,599–114,235,652, 54 basesExon 18: 114,236,981–114,237,034, 54 basesExon 19: 114,237,662–114,237,715, 54 basesExon 20: 114,240,220–114,240,273, 54 basesExon 21: 114,240,434–114,240,487, 54 basesExon 22: 114,242,187–114,242,231, 45 basesExon 23: 114,243,507–114,243,560, 54 basesExon 24: 114,245,866–114,245,910, 45 basesExon 25: 114,250,615–114,250,668, 54 basesExon 26: 114,252,593–114,252,646, 54 basesExon 27: 114,252,879–114,252,932, 54 basesExon 28: 114,258,541–114,258,594, 54 basesExon 29: 114,264,355–114,264,408, 54 basesExon 30: 114,264,924–114,264,968, 45 basesExon 31: 114,265,066–114,265,110, 45 basesExon 32: 114,265,422–114,265,475, 54 basesExon 33: 114,266,565–114,266,618, 54 basesExon 34: 114,267,504–114,267,557, 54 basesExon 35: 114,269,241–114,269,294, 54 basesExon 36: 114,270,728–114,270,781, 54 basesExon 37: 114,275,661–114,275,768, 108 basesExon 38: 114,282,277–114,282,330, 54 basesExon 39: 114,282,457–114,282,564, 108 basesExon 40: 114,283,709–114,283,762, 54 basesExon 41: 114,284,724–114,284,777, 54 basesExon 42: 114,288,455–114,288,511, 57 basesExon 43: 114,288,702–114,288,755, 54 basesExon 44: 114,288,914–114,288,967, 54 basesExon 45: 114,289,242–114,289,295, 54 basesExon 46: 114,290,058–114,290,111, 54 basesExon 47: 114,290,224–114,290,331, 108 basesExon 48: 114,290,810–114,290,917, 108 basesExon 49: 114,292,103–114,292,210, 108 basesExon 50: 114,300,070–114,300,123, 54 basesExon 51: 114,300,625–114,300,687, 63 basesExon 52: 114,301,072–114,301,125, 54 basesExon 53: 114,301,284–114,301,319, 36 basesExon 54: 114,301,445–114,301,462, 18 basesExon 55: 114,301,682–114,301,717, 36 basesExon 56: 114,302,082–114,302,108, 27 basesExon 57: 114,304,608–114,304,673, 66 basesExon 58: 114,306,520–114,306,688, 169 basesExon 59: 114,307,669–114,307,778, 110 basesExon 60: 114,309,260–114,309,478, 219 basesExon 61: 114,310,549–114,312,511, 1,963 bases12550615′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 7.8 kb of the gene's 157 kb; 5,583 of those bases code for the protein.

How a genome test reads COL27A1

36

positions in COL27A1 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 157 kb of COL27A1, introns included, not only the 7.8 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). COL27A1 gene: collagen type XXVII alpha 1 chain. Retrieved 17 October 2026, from https://dantelabs.com/genes/col27a1

Vancouver

Dante Labs. COL27A1 gene: collagen type XXVII alpha 1 chain [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/col27a1

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