Trait
Decrease in jaw mobility
Clinical name: Trismus
Limitation in the ability to open the mouth.
Summary
- Also called
- Decrease in jaw movement, Decrease in jaw opening, Limited jaw mobility, Limited jaw movement, Limited jaw opening, Limited mouth opening, Lockjaw, Pain of muscles of mastication
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
Read the genes linked to Decrease in jaw mobility, and the rest of your genome, with one test.
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Get my Genome Test15 genes linked to Decrease in jaw mobility
Changes in these genes cause rare conditions in which Decrease in jaw mobility is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| AHDC1AT-hook DNA binding motif containing 1 | Always | In 1 condition |
| KCNC2potassium voltage-gated channel subfamily C member 2 | Always | In 1 condition |
| MYH8myosin heavy chain 8 | Always | In 2 conditions |
| HSPG2heparan sulfate proteoglycan 2 | Very often (80–99%) | In 1 condition |
| GBA1glucosylceramidase beta 1 | Often (30–79%) | In 2 conditions |
| LIFRLIF receptor subunit alpha | Often (30–79%) | In 1 condition |
| CLPBClpB family mitochondrial disaggregase | Sometimes (5–29%) | In 1 condition |
| COL2A1collagen type II alpha 1 chain | Sometimes (5–29%) | In 1 condition |
| PNKDPNKD metallo-beta-lactamase domain containing | Sometimes (5–29%) | In 1 condition |
| PRRT2proline rich transmembrane protein 2 | Sometimes (5–29%) | In 1 condition |
| CRLF1cytokine receptor like factor 1 | Not recorded | In 1 condition |
| EDNRAendothelin receptor type A | Not recorded | In 1 condition |
| MYMKmyomaker, myoblast fusion factor | Not recorded | In 1 condition |
| SF3B4splicing factor 3b subunit 4 | Not recorded | In 1 condition |
| TPM2tropomyosin 2 | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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