Trait
Moderate visual impairment
Clinical name: Moderately reduced visual acuity
Moderate reduction of the ability to see. On the 6m visual acuity scale, moderate reduction is defined as less than 6/18 but at least 6/60. On the 20ft visual acuity scale, moderate reduction is defined as less than 20/70 but at least 20/200. On the decimal visual acuity scale, moderate reduction is defined as less than 0.3 but at least 0.1.
Summary
- Also called
- Moderate reduction in visual acuity, Moderate vision loss, Moderate visual loss
- Body system
- Abnormality of the eye
Reference genomeGRCh38hg38
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Get my Genome Test15 genes linked to Moderate visual impairment
Changes in these genes cause rare conditions in which Moderate visual impairment is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| CFAP20cilia and flagella associated protein 20 | Always | In 1 condition |
| CNGB3cyclic nucleotide gated channel subunit beta 3 | Always | In 1 condition |
| FDXRferredoxin reductase | Always | In 1 condition |
| PIGAphosphatidylinositol glycan anchor biosynthesis class A | Always | In 1 condition |
| RPGRIP1RPGR interacting protein 1 | Always | In 2 conditions |
| TMEM216transmembrane protein 216 | Always | In 1 condition |
| AHRaryl hydrocarbon receptor | Often (30–79%) | In 1 condition |
| DNM1Ldynamin 1L | Often (30–79%) | In 1 condition |
| IMPG1interphotoreceptor matrix proteoglycan 1 | Often (30–79%) | In 1 condition |
| IMPG2interphotoreceptor matrix proteoglycan 2 | Often (30–79%) | In 1 condition |
| OPA1OPA1 mitochondrial dynamin like GTPase | Often (30–79%) | In 1 condition |
| PPIBpeptidylprolyl isomerase B | Often (30–79%) | In 1 condition |
| OTX2orthodenticle homeobox 2 | Sometimes (5–29%) | In 1 condition |
| RAC1Rac family small GTPase 1 | Sometimes (5–29%) | In 1 condition |
| LRP5LDL receptor related protein 5 | Rarely (1–4%) | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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