Trait
Lumbago
Clinical name: Low back pain
An unpleasant sensation characterized by physical discomfort (such as pricking, throbbing, or aching) localized to the lower back.
Summary
- Also called
- Lower back pain
Reference genomeGRCh38hg38
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Get my Genome Test17 genes linked to Lumbago
Changes in these genes cause rare conditions in which Lumbago is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| AEBP1AE binding protein 1 | Always | In 1 condition |
| PTCRApre T cell antigen receptor alpha | Always | In 1 condition |
| WRNWRN RecQ like helicase | Always | In 1 condition |
| ANXA11annexin A11 | Very often (80–99%) | In 1 condition |
| HGDhomogentisate 1,2-dioxygenase | Very often (80–99%) | In 1 condition |
| HLA-Bmajor histocompatibility complex, class I, B | Often (30–79%) | In 1 condition |
| MNX1motor neuron and pancreas homeobox 1 | Often (30–79%) | In 1 condition |
| NGFnerve growth factor | Often (30–79%) | In 1 condition |
| WASHC5WASH complex subunit 5 | Often (30–79%) | In 1 condition |
| ALDH18A1aldehyde dehydrogenase 18 family member A1 | Sometimes (5–29%) | In 1 condition |
| BNC2basonuclin zinc finger protein 2 | Sometimes (5–29%) | In 1 condition |
| MEFVMEFV innate immunity regulator, pyrin | Sometimes (5–29%) | In 1 condition |
| NAB2NGFI-A binding protein 2 | Rarely (1–4%) | In 1 condition |
| STAT6signal transducer and activator of transcription 6 | Rarely (1–4%) | In 1 condition |
| HTRA1HtrA serine peptidase 1 | Not recorded | In 1 condition |
| SPASTspastin | Not recorded | In 1 condition |
| TBX6T-box transcription factor 6 | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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