Trait
Choroidal neovascularization
Choroidal neovascularization (CNV) is the inward growth of new blood vessels arising from the choriocapillaris. Depending on the stage of development, they can be external (type 1 NV) or internal (type 2 NV) to the retinal pigment epithelium.
Summary
- Also called
- Choroidal neovascular membrane
- Body system
- Abnormality of the eye
Reference genomeGRCh38hg38
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Get my Genome Test23 genes linked to Choroidal neovascularization
Changes in these genes cause rare conditions in which Choroidal neovascularization is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| ABCC6ATP binding cassette subfamily C member 6 | Often (30–79%) | In 3 conditions |
| C1QTNF5C1q and TNF related 5 | Often (30–79%) | In 2 conditions |
| CFIcomplement factor I | Often (30–79%) | In 2 conditions |
| CLEC3BC-type lectin domain family 3 member B | Often (30–79%) | In 1 condition |
| FBLN1fibulin 1 | Often (30–79%) | In 1 condition |
| TIMP3TIMP metallopeptidase inhibitor 3 | Often (30–79%) | In 1 condition |
| XYLT1xylosyltransferase 1 | Often (30–79%) | In 1 condition |
| XYLT2xylosyltransferase 2 | Often (30–79%) | In 1 condition |
| CFHcomplement factor H | Sometimes (5–29%) | In 1 condition |
| CHMCHM Rab escort protein | Sometimes (5–29%) | In 1 condition |
| CLCN2chloride voltage-gated channel 2 | Sometimes (5–29%) | In 1 condition |
| EFEMP1EGF-like fibulin extracellular matrix protein 1 | Sometimes (5–29%) | In 1 condition |
| ENPP1ectonucleotide pyrophosphatase/phosphodiesterase 1 | Sometimes (5–29%) | In 2 conditions |
| FBN2fibrillin 2 | Sometimes (5–29%) | In 1 condition |
| HLA-Amajor histocompatibility complex, class I, A | Sometimes (5–29%) | In 1 condition |
| APOEapolipoprotein E | Rarely (1–4%) | In 1 condition |
| CFHR1complement factor H related 1 | Rarely (1–4%) | In 1 condition |
| CFHR3complement factor H related 3 | Rarely (1–4%) | In 1 condition |
| HMCN1hemicentin 1 | Rarely (1–4%) | In 1 condition |
| MAPKAPK3MAPK activated protein kinase 3 | Rarely (1–4%) | In 1 condition |
| PRPH2peripherin 2 | Rarely (1–4%) | In 2 conditions |
| AGXTalanine--glyoxylate aminotransferase | Not recorded | In 1 condition |
| FBLN5fibulin 5 | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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