Gene
TBX15
T-box transcription factor 15
- HGNC 11594↗(opens in a new tab)
- Ensembl gene ENSG00000092607↗(opens in a new tab)
- NCBI Gene 6913↗(opens in a new tab)
Summary
- Cytogenetic location
- 1p12
- Coordinates
- Chromosome 1: 118,883,047–118,988,343 (GRCh38)
- Exons
- 8 exons across 105.3 kb
- Protein
- 602 amino acids
- Previous symbols
- TBX14
- MANE Select transcript
- ENST00000369429.5NM_001330677.2
- Locus type
- gene with protein product
- Very high
- Confident
- Low
- Very low
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
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How TBX15 is laid out
- Coding sequence
- Untranslated region
- Intron
- Direction of transcription
- Stretches short reads find hard
Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.
Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).
Nearby genes from Ensembl release 116, on GRCh38.
Exons make up 4 kb of the gene's 105.3 kb; 1,809 of those bases code for the protein.
Traits linked to TBX15
The Human Phenotype Ontology lists these as features of the rare conditions TBX15 can cause. Each trait's page lists the other genes linked to it.
Abnormality of limbs
- Abnormality of the joint spaces of the elbow
- Dislocated hip since birth
- Elbow flexion contracture
- Fusion of upper and lower arm bones
- Hip dislocation
- Mesomelic leg shortening
- Short fingers or toes
- Short thighbone
Show 11 more traits
- Absent calf bone
- Absent proximal finger flexion creases
- Club feet
- Curvature of little finger
- Dislocated radial head
- Disproportionately short middle portion of limb
- Disproportionately short upper portion of limb
- Joint contracture of the hand
- Webbed 2nd and 3rd toes
- Webbed 4th-5th toes
- Wrist flexion contracture
Abnormality of the musculoskeletal system
- Hypoplastic iliac wing
- Small shoulder blade
- Small wings of the pelvic girdle
- Anterior rounding of vertebral bodies
- Bell-shaped thorax
- Hypoplastic ischia
- Hypoplastic pubic bone
- Large tailbone
Show 2 more traits
External links
Gene records
Transcript
Protein
Where this comes from
- HGNC: the gene's symbol, name, other symbols and location.
- MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
- The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
Cite this page
Dante Labs. (n.d.). TBX15 gene: T-box transcription factor 15. Retrieved 17 October 2026, from https://dantelabs.com/genes/tbx15
Dante Labs. TBX15 gene: T-box transcription factor 15 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/tbx15
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