Trait
Wrist flexion contracture
A chronic loss of wrist joint motion due to structural changes in muscle, tendons, ligaments, or skin that prevent normal movement of the joints of the wrist.
Summary
- Also called
- Wrist contracture, Wrist flexion deformity
Reference genomeGRCh38hg38
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Get my Genome Test37 genes linked to Wrist flexion contracture
Changes in these genes cause rare conditions in which Wrist flexion contracture is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| B3GALT6beta-1,3-galactosyltransferase 6 | Always | In 1 condition |
| DSTdystonin | Always | In 1 condition |
| ERCC1ERCC excision repair 1, endonuclease non-catalytic subunit | Always | In 1 condition |
| MECP2methyl-CpG binding protein 2 | Always | In 1 condition |
| MUSKmuscle associated receptor tyrosine kinase | Always | In 1 condition |
| FILIP1filamin A interacting protein 1 | Very often (80–99%) | In 1 condition |
| MYH3myosin heavy chain 3 | Very often (80–99%) | In 1 condition |
| COL12A1collagen type XII alpha 1 chain | Often (30–79%) | In 1 condition |
| COL25A1collagen type XXV alpha 1 chain | Often (30–79%) | In 1 condition |
| COL6A1collagen type VI alpha 1 chain | Often (30–79%) | In 1 condition |
| COL6A2collagen type VI alpha 2 chain | Often (30–79%) | In 1 condition |
| COL6A3collagen type VI alpha 3 chain | Often (30–79%) | In 1 condition |
| DDR2discoidin domain receptor tyrosine kinase 2 | Often (30–79%) | In 1 condition |
| ERGIC1endoplasmic reticulum-golgi intermediate compartment 1 | Often (30–79%) | In 1 condition |
| FLNAfilamin A | Often (30–79%) | In 2 conditions |
| HSPG2heparan sulfate proteoglycan 2 | Often (30–79%) | In 2 conditions |
| MAP3K7mitogen-activated protein kinase kinase kinase 7 | Often (30–79%) | In 1 condition |
| MYL11myosin light chain 11 | Often (30–79%) | In 1 condition |
| SCYL2SCY1 like pseudokinase 2 | Often (30–79%) | In 1 condition |
| TNNT1troponin T1, slow skeletal type | Often (30–79%) | In 1 condition |
| ADGRG6adhesion G protein-coupled receptor G6 | Sometimes (5–29%) | In 1 condition |
| ANO5anoctamin 5 | Sometimes (5–29%) | In 1 condition |
| CADM3cell adhesion molecule 3 | Sometimes (5–29%) | In 1 condition |
| CAPN3calpain 3 | Sometimes (5–29%) | In 1 condition |
| DHX16DEAH-box helicase 16 | Sometimes (5–29%) | In 1 condition |
| DLK1delta like non-canonical Notch ligand 1 | Sometimes (5–29%) | In 1 condition |
| ESCO2establishment of sister chromatid cohesion N-acetyltransferase 2 | Sometimes (5–29%) | In 2 conditions |
| FBN2fibrillin 2 | Sometimes (5–29%) | In 1 condition |
| LMNAlamin A/C | Sometimes (5–29%) | In 1 condition |
| MEG3maternally expressed 3 | Sometimes (5–29%) | In 1 condition |
| RTL1retrotransposon Gag like 1 | Sometimes (5–29%) | In 1 condition |
| SPG11SPG11 vesicle trafficking associated, spatacsin | Sometimes (5–29%) | In 1 condition |
| TUBB3tubulin beta 3 class III | Sometimes (5–29%) | In 1 condition |
| ADAMTSL2ADAMTS like 2 | Not recorded | In 1 condition |
| MMP2matrix metallopeptidase 2 | Not recorded | In 1 condition |
| PRG4proteoglycan 4 | Not recorded | In 1 condition |
| TBX15T-box transcription factor 15 | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
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Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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