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Gene

TAMM41

TAM41 mitochondrial translocator assembly and maintenance homolog

Summary

Cytogenetic location
3p25.2
Coordinates
Chromosome 3: 11,790,442–11,846,885 (GRCh38)
Exons
8 exons across 56.4 kb
Protein
337 amino acids
Also known as
MGC16471, DKFZp434E0519
Previous symbols
C3orf31
MANE Select transcript
ENST00000455809.6NM_001284401.2
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Curated report relevant to this gene

  • Primary Mitochondrial Disease

    • Combined Oxidative Phosphorylation Deficiency

      Disorders, usually caused by nuclear genes involved in mitochondrial protein production, that reduce several respiratory chain complexes at once and often cause severe multisystem disease in childhood.

      • 2 GenCC submitters rate it definitive or strong
      What knowing changes

      Knowing can end a diagnostic search and guide surveillance and supportive care.

How TAMM41 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 3, with a bracket where TAMM41 sits. TAMM41 and 5 genes near it on chromosome 3, from 11,318,664 to 12,318,663.Chromosome 33p25.2p26.3p26.2p26.1p25.3p25.2p25.1p24.3p24.2p24.1p23p22.3p22.2p22.1p21.33p21.32p21.31p21.2p21.1p14.3p14.2p14.1p13p12.3p12.2p12.1p11.2p11.1q11.1q11.2q12.1q12.2q12.3q13.11q13.12q13.13q13.2q13.31q13.32q13.33q21.1q21.2q21.3q22.1q22.2q22.3q23q24q25.1q25.2q25.31q25.32q25.33q26.1q26.2q26.31q26.32q26.33q27.1q27.2q27.3q28q2911.4 Mb11.6 Mb11.8 Mb12 Mb12.2 MbATG7: 11,272,309–11,557,665, forward strandATG7VGLL4: 11,556,069–11,771,350, reverse strandVGLL4TAMM41: 11,790,442–11,846,885, reverse strandTAMM41SYN2: 12,004,325–12,192,032, forward strandSYN2TIMP4: 12,149,834–12,159,395, reverse strandTIMP4PPARG: 12,287,368–12,455,622, forward strandPPARGDiagram of TAMM41: 8 exons on the reverse strand of chromosome 3Exon 8: 11,790,442–11,790,581, 140 basesExon 7: 11,807,833–11,807,895, 63 basesExon 6: 11,809,517–11,809,682, 166 basesExon 5: 11,817,192–11,817,337, 146 basesExon 4: 11,829,714–11,829,864, 151 basesExon 3: 11,839,222–11,839,314, 93 basesExon 2: 11,844,029–11,844,211, 183 basesExon 1: 11,846,502–11,846,885, 384 bases876543215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 1.3 kb of the gene's 56.4 kb; 1,014 of those bases code for the protein.

How a genome test reads TAMM41

1

position in TAMM41 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 56.4 kb of TAMM41, introns included, not only the 1.3 kb of exons.

Genes linked to the same conditions

Traits linked to TAMM41

The Human Phenotype Ontology lists these as features of the rare conditions TAMM41 can cause. Each trait's page lists the other genes linked to it.

External links

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • GenCC and ClinGen, released 2026-10-16: which conditions the gene is linked to, and how strongly.
  • The ACMG secondary findings list, SF v3.2.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). TAMM41 gene: TAM41 mitochondrial translocator assembly and maintenance homolog. Retrieved 17 October 2026, from https://dantelabs.com/genes/tamm41

Vancouver

Dante Labs. TAMM41 gene: TAM41 mitochondrial translocator assembly and maintenance homolog [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/tamm41

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